NIH-funded research Career grant

A brief treatment for anxiety disorders and PTSD in South Africa

Official title: Brief Transdiagnostic Treatment for Anxiety Disorders and PTSD in South Africa: A Hybrid-Effectiveness Trial

Funded at Massachusetts General Hospital · NIH-10892939 · Data updated 2026-11-12

This study is testing a new, shorter treatment for anxiety and PTSD that can be used in regular doctor’s offices in South Africa, making it easier for people to get the help they need.

More Anxiety research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 23, 2021
Project endJuly 31, 2026
Funding year2024
Award (this year)$182,948
NIH project number5K01TW012180-04
Project IDNIH-10892939 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals in South Africa experiencing anxiety disorders or PTSD who have limited access to traditional mental health treatments.

Less likely to help

Patients with severe mental health conditions requiring intensive or specialized care may not benefit from this brief treatment approach.

What this research studies

This research investigates a brief treatment approach for anxiety disorders and PTSD, specifically designed for primary care settings in South Africa. The treatment, known as False Safety Behavior Elimination Treatment (F-SET), aims to overcome barriers to care by being shorter, culturally appropriate, and easier to administer than traditional evidence-based treatments. By focusing on multiple disorders simultaneously, this approach seeks to increase access to effective mental health care for individuals who currently lack treatment options. The study will evaluate the effectiveness of this treatment in real-world clinical settings.

Why it matters

Potential benefit: If successful, this research could significantly improve access to effective mental health care for individuals suffering from anxiety disorders and PTSD in low and middle-income countries.

How similar studies have gone: Previous research has shown promise in using brief, transdiagnostic treatments for anxiety and PTSD, indicating potential for success in this novel application.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Korte, Kristina Jo — Massachusetts General Hospital
  • Study coordinator: Korte, Kristina Jo

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.