3D Ultrasonography to Measure Vitreous Structure and Movement over Time
Official title: 3-D Volumetric & 4-D Dynamic Ultrasonography to Quantify Vitreous Structure and Mobility
Funded at Weill Medical Coll of Cornell Univ · NIH-11342618 · Data updated 2026-11-12
A study using advanced ultrasound to quantify how the vitreous inside the eye changes with age and myopia, helping doctors understand how floaters and vision can be affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 15, 2026 |
| Project end | June 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $627,118 |
| NIH project number | 1R01EY038751-01 |
| Project ID | NIH-11342618 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with aging-related or myopic eye changes who are willing to undergo advanced ocular ultrasound imaging.
✕Less likely to help
Patients without vitreous changes or who cannot undergo the imaging procedure may not benefit from this study.
What this research studies
This project will use a 15-MHz ultrasound system to capture 3D and 4D data of the vitreous body. By measuring echodensity and mobility, researchers aim to describe how aging and nearsightedness alter the vitreous gel, its adhesion to the retina, and the risk of posterior vitreous detachment. The findings could illuminate why floaters degrade vision and how these changes might lead to retinal complications. Participating patients would contribute imaging data and may benefit from improved understanding of their eye health.
Why it matters
Potential benefit: If successful, this work could lead to better prediction and management of floaters and related retinal risks.
How similar studies have gone: Previous research has shown that quantitative imaging can reveal vitreous changes, but this project advances 3D/4D measurement for deeper insights.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Ketterling, Jeffrey — Weill Medical Coll of Cornell Univ
- Study coordinator: Ketterling, Jeffrey
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.