Drug or treatment

Siltuximab clinical trials

• 5Clinical trials
• 2Countries

Newest trials

All recruiting trials (5)

• Siltuximab treatment for CRS and ICANS after CAR‑T in multiple myeloma

  We will test whether siltuximab helps adults with multiple myeloma who develop CRS or ICANS after receiving CAR‑T therapy.

  Recruiting Phase 2 Institute of Hematology & Blood Diseases Hospital, China · Tianjin · NCT07106671

• Siltuximab for antibody-mediated rejection after lung transplant

  This study will test whether adding siltuximab, an IL‑6 blocker, to standard treatment is safe and tolerable for adults hospitalized with antibody-mediated rejection after lung transplant.

  Recruiting at 2 sites Phase 1 Washington University School of Medicine · St Louis, Missouri and 1 other locations · NCT06990711

• Combining Siltuximab with Melphalan for Multiple Myeloma Patients Undergoing Stem Cell Transplant

  This study is testing if combining a new drug called siltuximab with a standard treatment for multiple myeloma can help patients feel better after a stem cell transplant.

  Recruiting at 7 sites Phase 2 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT06679829

• Using siltuximab to prevent severe side effects during cancer treatment

  This study is testing if the drug siltuximab can help prevent severe side effects in cancer patients who are getting immune therapy again.

  Recruiting Phase 2 Ohio State University Comprehensive Cancer Center · Columbus, Ohio · NCT06470971

• Preventing cytokine release syndrome with siltuximab before epcoritamab treatment

  This study is testing if giving siltuximab before treatment with epcoritamab can help prevent serious side effects in people with large B-cell lymphoma or follicular lymphoma.

  Recruiting Phase 1 Case Comprehensive Cancer Center · Cleveland, Ohio · NCT06447376

Quick answers

How many clinical trials of Siltuximab are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (4 trials), China (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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