Drug or treatment

Avelumab clinical trials

• 9Clinical trials
• 8Countries

Newest trials

All recruiting trials (9)

• Cisplatin chemotherapy followed by maintenance avelumab for upper tract urothelial carcinoma

  This trial will try maintenance avelumab after adjuvant cisplatin chemotherapy to see if it reduces recurrence in adults with high-risk, surgically removed upper tract urothelial carcinoma who are disease‑free after chemo.

  Recruiting Phase 2 Samsung Medical Center · Seoul, Gangnam · NCT07225374

• Enfortumab vedotin plus avelumab as first-line treatment for advanced penile cancer

  This trial tests whether combining enfortumab vedotin with avelumab helps men with advanced or metastatic penile squamous cell carcinoma as first-line treatment.

  Recruiting at 9 sites Phase 2 Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest · Dresden and 8 other locations · NCT07110038

• Comparing 3 vs 6 cycles of chemotherapy followed by avelumab for advanced bladder cancer

  This study is testing whether giving 3 or 6 cycles of chemotherapy followed by avelumab can improve the quality of life for people with advanced bladder cancer.

  Recruiting at 2 sites Phase 2 Queen Mary University of London · Paris and 2 other locations · NCT06892860

• Combining chemotherapy with cetuximab and avelumab for advanced head and neck cancer

  This study is testing a new treatment plan that combines chemotherapy with two medications, cetuximab and avelumab, to see if it helps people with advanced head and neck cancer live longer without their disease getting worse.

  Recruiting at 3 sites Phase 2 Gruppo Oncologico del Nord-Ovest · Cagliari, CAGLIARI and 7 other locations · NCT06869473

• Tetra-modality bladder-preservation approach in muscle-invasive bladder cancer

  This trial tests whether adding the immunotherapy drug avelumab to tumor removal, chemotherapy, and radiation can help people with muscle-invasive bladder cancer keep their bladder.

  Recruiting Phase 2 American University of Beirut Medical Center · Beirut, Beirut · NCT06686381

• Combining Avelumab with Standard Chemotherapy for Advanced Head and Neck Cancer

  This study is testing if adding avelumab to standard chemotherapy can help people with advanced head and neck cancer live longer and feel better.

  Recruiting Phase 2 Groupe Oncologie Radiotherapie Tete et Cou · Vandœuvre-lès-Nancy · NCT06640725

• Combining Lurbinectedin and Avelumab for Small Cell Carcinoma of the Bladder

  This study is testing if a combination of two drugs, lurbinectedin and avelumab, can help people with small cell carcinoma of the bladder and similar tumors feel better when their cancer has come back or spread.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT06228066

• Combination of Talazoparib and Avelumab for Urothelial Carcinoma Maintenance Therapy

  This study is testing if a combination of two drugs, Talazoparib and Avelumab, can help people with advanced bladder cancer stay healthy longer after their initial chemotherapy.

  Recruiting at 11 sites Phase 2 Centre Francois Baclesse · Angers and 13 other locations · NCT04678362

• Using Avelumab and Methotrexate to Treat Low-risk Gestational Trophoblastic Neoplasias

  This study is testing if combining avelumab with methotrexate can help women with low-risk gestational trophoblastic neoplasias feel better and have fewer side effects than standard chemotherapy.

  Recruiting at 6 sites Phase 1/2 Hospices Civils de Lyon · Pierre-Bénite, Pierre Bénite and 8 other locations · NCT04396223

Quick answers

How many clinical trials of Avelumab are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in France (4 trials), South Korea (1 trial), Lebanon (1 trial), Germany (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 8, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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