Drug or treatment

Avapritinib clinical trials

• 9Clinical trials
• 9Countries

Newest trials

All recruiting trials (9)

• Observing avapritinib treatment in people with indolent systemic mastocytosis in Germany

  This study will see if avapritinib helps manage symptoms in people with indolent systemic mastocytosis who are starting the drug as part of routine care in Germany.

  Recruiting at 12 sites Blueprint Medicines Corporation · Berlin and 11 other locations · NCT07255638

• Avapritinib with standard chemotherapy for newly diagnosed KIT‑mutant CBF‑AML

  This will test whether adding avapritinib to standard induction and consolidation therapies helps adults newly diagnosed with KIT‑mutated core‑binding factor AML achieve deeper remissions and live longer.

  Recruiting Phase 1/2 The First Affiliated Hospital of Soochow University · Suzhou, Jiangsu · NCT07028073

• Combining avapritinib, azacitidine, and venetoclax for treating relapsed AML after stem cell transplant

  This study is testing a new combination of three medications to see if they can help people with relapsed acute myeloid leukemia feel better after a stem cell transplant.

  Recruiting Phase 2 Institute of Hematology & Blood Diseases Hospital, China · Tianjin · NCT06783790

• Long-term safety evaluation of avapritinib for mastocytosis patients

  This study is testing the long-term safety of avapritinib for patients with mastocytosis who have already benefited from the treatment in a previous study.

  Recruiting at 8 sites Phase 4 Blueprint Medicines Corporation · Edegem and 7 other locations · NCT06748001

• Combining avapritinib and decitabine for treating systemic mastocytosis with associated hematologic neoplasm

  This study is testing a new combination treatment of avapritinib and decitabine to see if it can help people with systemic mastocytosis and related blood cancers feel better and manage their condition more effectively.

  Recruiting at 2 sites Phase 1 H. Lee Moffitt Cancer Center and Research Institute · Phoenix, Arizona and 6 other locations · NCT06327685

• Using Avapritinib to treat relapsed or refractory pediatric CBF-AML with KIT mutation

  This study is testing if a new drug called avapritinib can help children with a specific type of leukemia that keeps coming back and has a certain mutation, to see if it works better than the treatments they currently have.

  Recruiting Phase 2 Children's Hospital of Soochow University · Hefei, Anhui and 11 other locations · NCT06316960

• Evaluating Avapritinib for Advanced Gastrointestinal Stromal Tumors

  This study is testing if Avapritinib can help people with advanced gastrointestinal stromal tumors feel better and improve their health in real-world situations.

  Recruiting First Affiliated Hospital, Sun Yat-Sen University · Guangzhou · NCT05464875

• Using Avapritinib for treating specific types of gastrointestinal stromal tumors

  This study is testing if Avapritinib can help people with hard-to-treat gastrointestinal stromal tumors that have specific gene mutations feel better and live longer.

  Recruiting First Affiliated Hospital, Sun Yat-Sen University · Guangzhou · NCT05461664

• Avapritinib for treating advanced solid tumors with specific mutations

  This study is testing if a new drug called avapritinib can help people with advanced solid tumors that have specific mutations feel better and live longer after other treatments haven't worked.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT04771520

Quick answers

How many clinical trials of Avapritinib are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in China (5 trials), United States (2 trials), Germany (2 trials), Belgium (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1: 1, Phase 1/2: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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