Condition
Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 clinical trials and research
As of November 12, 2026, Find a Trial lists 4 Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 clinical trials that are recruiting, at sites in 3 countries (most in United States (4), Canada (1), Puerto Rico (1)). By phase: Phase 3 (2), Phase 1/2 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 3Countries
Newest Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Shorter radiation course vs standard course for soft tissue sarcoma of the limb/trunk | Phase 3 | Birmingham, Alabama and 66 other locations | Recruiting | May 29, 2026 |
| Adding abemaciclib to gemcitabine chemotherapy for advanced soft tissue sarcoma | Phase 1/2 | Houston, Texas | Recruiting | Jul 12, 2024 |
| Combining immunotherapy with chemotherapy for aggressive sarcomas | Phase 3 | Phoenix, Arizona and 268 other locations | Recruiting | May 21, 2024 |
| Comparing limited and intense follow-up care for patients with stage II-III soft tissue sarcoma | Phase 2 | Houston, Texas | Recruiting | Feb 12, 2021 |
All recruiting trials (4)
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Shorter radiation course vs standard course for soft tissue sarcoma of the limb/trunk
This trial tests whether a 5-day, ultrahypofractionated radiation therapy approach works as well as the standard 25-day course for soft tissue sarcoma that can be surgically removed.
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Adding abemaciclib to gemcitabine chemotherapy for advanced soft tissue sarcoma
This phase 1/2 trial tests whether adding the targeted drug abemaciclib to gemcitabine is safe and works better than gemcitabine plus docetaxel for adults with advanced or metastatic leiomyosarcoma or dedifferentiated liposarcoma whose tumors are Rb-positive.
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Combining immunotherapy with chemotherapy for aggressive sarcomas
This study is testing if combining immunotherapy with chemotherapy can help people with aggressive sarcomas live longer and feel better compared to just using chemotherapy alone.
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Comparing limited and intense follow-up care for patients with stage II-III soft tissue sarcoma
This study is testing whether more frequent follow-up visits or fewer visits after surgery can help reduce anxiety and improve outcomes for patients with stage II-III soft tissue sarcoma.
Related topics
Quick answers
How many Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (4 trials), Canada (1 trial), Puerto Rico (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 2, Phase 1/2: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.