Condition
Shigella clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Shigella clinical trials that are recruiting, at sites in 3 countries (most in United States (2), Bangladesh (1), Zambia (1)). By phase: Phase 2 (2), Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 3Countries
Newest Shigella clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Azithromycin for treating non-bloody Shigella watery diarrhea in children | Phase 2 | Chāndpur and 3 other locations | Recruiting | Feb 25, 2026 |
| First-in-human dose escalation of the Shigella-04 vaccine in healthy young adults | Phase 1 | Cincinnati, Ohio | Recruiting | Oct 3, 2025 |
| Oral ShigETEC vaccine to prevent Shigella and ETEC infection in healthy adults | Phase 2 | Baltimore, Maryland | Recruiting | Jul 3, 2025 |
All recruiting trials (3)
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Azithromycin for treating non-bloody Shigella watery diarrhea in children
It will test whether giving azithromycin to children 6–59 months with Shigella-positive watery (non-bloody) diarrhea shortens the illness, clears the bacteria faster, and improves growth.
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First-in-human dose escalation of the Shigella-04 vaccine in healthy young adults
This test checks whether two intramuscular doses of the Shigella-04 vaccine are safe and produce an immune response in healthy adults ages 18 to 49.
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Oral ShigETEC vaccine to prevent Shigella and ETEC infection in healthy adults
This study will test whether an oral ShigETEC vaccine can protect healthy adults 18–50 from illness after deliberate exposure to Shigella flexneri.
Related topics
Quick answers
How many Shigella clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (2 trials), Bangladesh (1 trial), Zambia (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.