Condition
Severe Hypertriglyceridemia clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Severe Hypertriglyceridemia clinical trials that are recruiting, at sites in 28 countries (most in Canada (3), United States (3), China (2)). By phase: Phase 2 (2), Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 28Countries
Newest Severe Hypertriglyceridemia clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Ion775 for high triglyceride levels: safety, tolerability, and how well it works | Phase 2 | Lincoln, California and 17 other locations | Recruiting | May 22, 2026 |
| Solbinsiran injections to lower very high triglycerides | Phase 2 | Phoenix, Arizona and 40 other locations | Recruiting | Dec 8, 2025 |
| Plozasiran for adults with severe high triglycerides at risk of acute pancreatitis | Phase 3 | Los Angeles, California and 139 other locations | Recruiting | Mar 18, 2025 |
All recruiting trials (3)
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Ion775 for high triglyceride levels: safety, tolerability, and how well it works
A drug called ION775 is being tested to see if it can safely lower fasting triglycerides in adults with hypertriglyceridemia or severe hypertriglyceridemia who are already on standard lipid medicines.
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Solbinsiran injections to lower very high triglycerides
This trial will test whether two injections of solbinsiran can lower very high triglyceride levels in adults with severe hypertriglyceridemia.
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Plozasiran for adults with severe high triglycerides at risk of acute pancreatitis
This trial will test whether plozasiran injections every three months can lower triglycerides and reduce pancreatitis risk in adults with severe high triglycerides who have had multiple recent pancreatitis attacks.
Related topics
Quick answers
How many Severe Hypertriglyceridemia clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 28 countries. The most sites are in Canada (3 trials), United States (3 trials), China (2 trials), Argentina (1 trial), Austria (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.