Condition

Scleroderma, Systemic clinical trials and research

• 8Clinical trials
• 21Countries

Newest Scleroderma, Systemic clinical trials

All recruiting trials (8)

• First-in-human test of PRO-203 in healthy adults and people with systemic sclerosis

  Researchers will test a single subcutaneous dose of PRO-203 in healthy adults and in people with systemic sclerosis to see if it is safe and how the body handles it.

  Recruiting at 12 sites Phase 1/2 Prolium Bioscience, Inc · Melbourne, Victoria and 12 other locations · NCT07641634

• Anti-CD19 CAR T-cell therapy for severe systemic sclerosis that didn’t respond to standard treatment

  This study tests whether a patient’s own anti-CD19 CAR T-cells can help reduce skin thickening and other disease activity in adults with active, treatment-resistant systemic sclerosis.

  Recruiting Phase 2 University Hospital, Montpellier · Lille and 3 other locations · NCT07493395

• Western Sweden Systemic Sclerosis Project

  This project will collect blood, skin and DNA samples from people with systemic sclerosis in Western Sweden to try to find genes, proteins, and immune changes linked to how the disease starts and gets worse.

  Recruiting Sahlgrenska University Hospital · Gothenburg, Sweden · NCT07345052

• Biopsychosocial (BETY) exercise program for children and adults with scleroderma

  This project will test whether BETY, a biopsychosocial exercise program, helps children and adults with scleroderma improve physical function and psychosocial well-being.

  Recruiting Hacettepe University · Ankara, Altındağ · NCT07292961

• Diosmin for healing finger (digital) ulcers in scleroderma

  This study will test whether the pill diosmin can safely help heal open finger ulcers in people with systemic sclerosis.

  Recruiting at 5 sites Primus Pharmaceuticals · Calgary, Alberta and 4 other locations · NCT06256575

• Mouth bacteria in systemic sclerosis

  This project will test whether the bacteria living under the gums differ in adults with early systemic sclerosis compared with routine dental patients.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT06182293

• Evaluating belimumab for treating lung disease in systemic sclerosis

  This study is testing if belimumab can help improve lung function and overall quality of life for adults with lung disease caused by systemic sclerosis.

  Recruiting at 114 sites Phase 2/3 GlaxoSmithKline · Phoenix, Arizona and 133 other locations · NCT05878717

• Trichoscopy for scalp involvement in systemic scleroderma

  This study tests whether a quick, noninvasive scalp dermoscopy (trichoscopy) can detect scalp changes in adults with systemic scleroderma.

  Recruiting University Hospital, Lille · Lille · NCT04804930

Related topics

Quick answers

How many Scleroderma, Systemic clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 21 countries. The most sites are in France (4 trials), Australia (2 trials), China (2 trials), Mexico (2 trials), South Korea (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 1, Phase 2: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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