Condition

Relapsed Neuroblastoma clinical trials and research

• 7Clinical trials
• 7Countries

Newest Relapsed Neuroblastoma clinical trials

All recruiting trials (7)

• Dual-target GD2 and B7-H3 CAR-NK therapy for children and young adults with relapsed or refractory neuroblastoma

  This trial tries an off-the-shelf CAR-NK cell treatment that targets GD2 and B7-H3 for children and young adults whose high-risk neuroblastoma has returned or not responded to prior therapy.

  Recruiting Phase 1/2 Beijing Biotech · Shenzhen, Guangdong · NCT07502287

• Multi-arm platform for relapsed neuroblastoma

  This trial will try several drug combinations (including bevacizumab, dinutuximab beta, irinotecan, topotecan and temozolomide) to see if they help children and young adults with relapsed high‑risk neuroblastoma.

  Recruiting at 13 sites Phase 1/2 University of Birmingham · Sydney and 22 other locations · NCT07334301

• NKG2D.zeta-NK cells plus C7R.GD2.CAR-T cells for relapsed or refractory neuroblastoma or osteosarcoma

  This study tests a combination of modified NK cells and CAR-T cells to see if it can safely help patients with GD2-expressing relapsed or refractory neuroblastoma or osteosarcoma.

  Recruiting Phase 1 Baylor College of Medicine · Houston, Texas · NCT07211737

• Prolonged Naxitamab with irinotecan, temozolomide, and sargramostim for relapsed or refractory neuroblastoma

  This trial will test whether giving the immunotherapy Naxitamab more slowly, along with irinotecan, temozolomide, and sargramostim, reduces infusion side effects for people with relapsed or refractory neuroblastoma.

  Recruiting at 2 sites Phase 1 Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT07027748

• Treatment with CAR T cells for high-risk neuroblastoma in children

  This study is testing a new CAR T cell treatment for children with hard-to-treat neuroblastoma to see if it is safe and how well it works.

  Recruiting at 2 sites Phase 1/2 Boston Children's Hospital · Boston, Massachusetts and 1 other locations · NCT06803875

• Using PEEL-224 with Vincristine and Temozolomide for Pediatric Solid Tumors

  This study is testing a new treatment called PEEL-224, alone and with other drugs, to see if it can help children with tough-to-treat solid tumors like neuroblastoma and rhabdomyosarcoma.

  Recruiting at 7 sites Phase 1/2 Children's Hospital of Philadelphia · Los Angeles, California and 6 other locations · NCT06721689

• Using expanded gamma delta T cells with chemotherapy for treating relapsed neuroblastoma and osteosarcoma

  This study is testing if a new treatment using special immune cells along with chemotherapy can help children with relapsed neuroblastoma and osteosarcoma feel better and improve their chances of recovery.

  Recruiting Phase 1 Emory University · Atlanta, Georgia · NCT05400603

Related topics

Quick answers

How many Relapsed Neuroblastoma clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (5 trials), Australia (1 trial), Austria (1 trial), Belgium (1 trial), New Zealand (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 4, Phase 1: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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