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Regorafenib clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Regorafenib clinical trials that are recruiting, at sites in 2 countries (most in China (2), United States (1)). By phase: Early Phase 1 (1), Phase 3 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 2Countries
Newest Regorafenib clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| DC-CIK immune cell therapy combined with PD-1/CTLA-4 bispecific antibody and regorafenib for third-line advanced colorectal cancer | Early Phase 1 | Nanjing, Jiangsu | Recruiting | Jan 15, 2026 |
| Regorafenib and lorigerlimab once radiographic MRD after colorectal cancer therapy | Phase 2 | Houston, Texas | Recruiting | Jul 18, 2025 |
| Combining Regorafenib with Irinotecan Drug-Eluting Beads for Liver Metastases from Colorectal Cancer | Phase 3 | Guangdong, Guangzhou | Recruiting | Apr 3, 2023 |
All recruiting trials (3)
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DC-CIK immune cell therapy combined with PD-1/CTLA-4 bispecific antibody and regorafenib for third-line advanced colorectal cancer
This treatment tries to see if combining a patient's own DC-CIK immune cells with a PD-1/CTLA-4 bispecific antibody plus regorafenib helps people with advanced colorectal cancer who have already received standard therapies.
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Regorafenib and lorigerlimab once radiographic MRD after colorectal cancer therapy
This study tests whether the drug combo regorafenib plus lorigerlimab can clear ctDNA-detected residual cancer after standard colorectal cancer therapy in high-risk patients.
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Combining Regorafenib with Irinotecan Drug-Eluting Beads for Liver Metastases from Colorectal Cancer
This study is testing whether combining two treatments, regorafenib and irinotecan drug-eluting beads, can help people with liver cancer that has spread from colorectal cancer when other treatments haven't worked.
Related topics
Quick answers
How many Regorafenib clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in China (2 trials), United States (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Early Phase 1: 1, Phase 3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.