Condition

Refractory Chronic Cough clinical trials and research

• 5Clinical trials
• 4Countries

Newest Refractory Chronic Cough clinical trials

All recruiting trials (5)

• Nalbuphine ER for chronic cough in people with RCC

  This study tests whether extended-release nalbuphine helps people with unexplained, long-standing cough that hasn’t improved with other treatments.

  Recruiting at 21 sites Phase 2 Trevi Therapeutics · Kelowna, British Columbia and 20 other locations · NCT07671924

• BLU-5937 for Refractory Chronic Cough: 24-Week Test in Adults (China Extension)

  This study tests whether BLU-5937 can reduce 24-hour cough frequency in adults with refractory or unexplained chronic cough.

  Recruiting at 38 sites Phase 3 GlaxoSmithKline · Leshan, Sichuan and 37 other locations · NCT07650084

• Cough Management app for refractory or unexplained chronic cough

  This trial will see if using a smartphone Cough Management program plus a smartwatch for four weeks lowers coughing and improves quality of life in adults 21–80 with refractory or unexplained chronic cough.

  Recruiting Hyfe Inc · Wilmington, Delaware · NCT07070895

• Behavioral Cough Suppression Therapy with or without an inhaled aid for refractory chronic cough

  This study tests whether adding an inhaled substance to behavioral cough suppression helps people with persistent chronic cough see if it works better than behavior therapy alone.

  Recruiting at 2 sites Phase 2 University of Montana · Aurora, Colorado and 2 other locations · NCT06960759

• Testing Duloxetine and Amitriptyline for Chronic Cough Relief

  This study is testing if two medications, Duloxetine and Amitriptyline, can help people with a stubborn chronic cough feel better.

  Recruiting Phase 2 Mayo Clinic · Rochester, Minnesota · NCT05110144

Related topics

Quick answers

How many Refractory Chronic Cough clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (3 trials), China (1 trial), Canada (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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