Condition
Recurrent Transformed Chronic Lymphocytic Leukemia clinical trials and research
As of November 12, 2026, Find a Trial lists 6 Recurrent Transformed Chronic Lymphocytic Leukemia clinical trials that are recruiting, in United States. By phase: Phase 1 (4), Phase 2 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 6Clinical trials
- 1Country
Newest Recurrent Transformed Chronic Lymphocytic Leukemia clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Zanubrutinib with odronextamab for Richter's transformation | Phase 1 | Duarte, California | Recruiting | Dec 16, 2024 |
| Treatment using modified T-cells for relapsed or refractory B-cell cancers | Phase 1 | Jacksonville, Florida | Recruiting | Jan 5, 2024 |
| Combining zanubrutinib and CAR T-cell therapy for treating Richter's syndrome | Phase 2 | New York, New York and 2 other locations | Recruiting | May 24, 2023 |
| Treatment for relapsed or refractory diffuse large B-cell lymphoma | Phase 2 | Duarte, California | Recruiting | Jan 5, 2023 |
| Genetically engineered CAR T-cells for treating certain blood cancers | Phase 1 | Columbus, Ohio and 1 other locations | Recruiting | Jun 14, 2022 |
| CD19 CAR-T cell therapy for treating relapsed B cell cancers | Phase 1 | Rochester, Minnesota | Recruiting | May 19, 2021 |
All recruiting trials (6)
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Zanubrutinib with odronextamab for Richter's transformation
This phase I test will see if combining zanubrutinib with odronextamab helps adults whose chronic lymphocytic leukemia has transformed into aggressive lymphoma (Richter's transformation).
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Treatment using modified T-cells for relapsed or refractory B-cell cancers
This study is testing a new treatment that uses specially modified T-cells to see if it can help people with hard-to-treat B-cell cancers.
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Combining zanubrutinib and CAR T-cell therapy for treating Richter's syndrome
This study is testing if combining zanubrutinib with CAR T-cell therapy can help people with Richter's syndrome, which is when chronic lymphocytic leukemia turns into a more aggressive lymphoma.
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Treatment for relapsed or refractory diffuse large B-cell lymphoma
This study is testing a new combination of two treatments for people with relapsed or hard-to-treat diffuse large B-cell lymphoma to see if it helps them respond better and live longer.
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Genetically engineered CAR T-cells for treating certain blood cancers
This study is testing a new type of treatment using specially modified immune cells to see if they can help people with certain blood cancers that haven't responded to other treatments.
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CD19 CAR-T cell therapy for treating relapsed B cell cancers
This study is testing a new treatment using modified immune cells to see if it can help people with relapsed B cell cancers feel better.
Related topics
Quick answers
How many Recurrent Transformed Chronic Lymphocytic Leukemia clinical trials are recruiting right now?
6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 4, Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.