Condition
Primary Hyperoxaluria Type 1 clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Primary Hyperoxaluria Type 1 clinical trials that are recruiting, at sites in 11 countries (most in United States (2), China (1), France (1)). By phase: Phase 2 (2), Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 11Countries
Newest Primary Hyperoxaluria Type 1 clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Single-dose test of YOLT-203 in PH1 patients | Phase 1 | Shanghai, Shanghai Municipality | Recruiting | Aug 20, 2026 |
| YOLT-203 for Primary Hyperoxaluria Type 1: 6+ years old to adults | Phase 2 | Birmingham, Alabama and 3 other locations | Recruiting | May 14, 2026 |
| Evaluating DCR-PHXC for patients with Primary Hyperoxaluria Type 1 and severe kidney disease | Phase 2 | San Francisco, California and 17 other locations | Recruiting | Oct 8, 2020 |
All recruiting trials (3)
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Single-dose test of YOLT-203 in PH1 patients
This study tests a single dose of YOLT-203 in people with Primary Hyperoxaluria Type 1 to see if it is safe and whether it lowers urinary oxalate.
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YOLT-203 for Primary Hyperoxaluria Type 1: 6+ years old to adults
This study tests YOLT-203 versus placebo in children and adults with Primary Hyperoxaluria Type 1 to see if it safely reduces oxalate and improves symptoms.
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Evaluating DCR-PHXC for patients with Primary Hyperoxaluria Type 1 and severe kidney disease
This study is testing a new treatment called DCR-PHXC to see if it can help people with Primary Hyperoxaluria Type 1 and severe kidney disease feel better.
Related topics
Quick answers
How many Primary Hyperoxaluria Type 1 clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 11 countries. The most sites are in United States (2 trials), China (1 trial), France (1 trial), Germany (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.