Condition
Plaque, Amyloid clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Plaque, Amyloid clinical trials that are recruiting, at sites in 4 countries (most in Japan (3), United States (3), China (2)). By phase: Phase 1 (2), Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 4Countries
Newest Plaque, Amyloid clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Testing LY4405094 in healthy people and people with Alzheimer’s disease | Phase 1 | Anaheim, California and 17 other locations | Recruiting | Aug 26, 2026 |
| Test of amyloid-targeting medicines in healthy people and adults with Alzheimer’s | Phase 1 | Anaheim, California and 18 other locations | Recruiting | Aug 26, 2026 |
| Donanemab follow-up dosing in participants who previously completed TRAILBLAZER-ALZ 3-EXT | Phase 3 | Phoenix, Arizona and 61 other locations | Recruiting | May 22, 2026 |
All recruiting trials (3)
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Testing LY4405094 in healthy people and people with Alzheimer’s disease
This study tests LY4405094 to see if it is safe and how it behaves in the body, including how it reaches the brain fluid in healthy participants and how it affects a brain protein in people with Alzheimer's disease.
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Test of amyloid-targeting medicines in healthy people and adults with Alzheimer’s
This trial tests the safety and tolerability of amyloid-targeting drugs, plus a placebo, in healthy adults and in people with Alzheimer’s disease to see if the drugs can reduce brain amyloid plaques.
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Donanemab follow-up dosing in participants who previously completed TRAILBLAZER-ALZ 3-EXT
This study tests whether giving annual donanemab doses benefits people with Alzheimer's disease who finished the prior trial.
Related topics
Quick answers
How many Plaque, Amyloid clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in Japan (3 trials), United States (3 trials), China (2 trials), Puerto Rico (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.