Drug or treatment

Donanemab clinical trials

• 5Clinical trials
• 7Countries

Newest trials

All recruiting trials (5)

• Donanemab follow-up dosing in participants who previously completed TRAILBLAZER-ALZ 3-EXT

  This study tests whether giving annual donanemab doses benefits people with Alzheimer's disease who finished the prior trial.

  Recruiting at 60 sites Phase 3 Eli Lilly and Company · Phoenix, Arizona and 61 other locations · NCT07602582

• Donanemab in Early Cognitive Decline with Lewy Body Features (TRAILBLAZER-ALZ 7)

  This trial tests donanemab versus placebo to see if it can slow thinking and daily-function decline in people with early cognitive decline and Lewy body disease features.

  Recruiting at 47 sites Phase 2 Eli Lilly and Company · Chandler, Arizona and 71 other locations · NCT07589595

• Donanemab in Chinese adults at risk for Alzheimer’s decline

  This study tests donanemab versus placebo in Chinese adults who are cognitively unimpaired but show early signs suggesting they may decline due to Alzheimer’s disease.

  Recruiting at 30 sites Phase 3 Eli Lilly and Company · Beijing and 29 other locations · NCT07571161

• Donanemab and RG6289 in PSEN1 E280A Mutation Carriers with autosomal-dominant Alzheimer’s disease

  Aimed at people with the PSEN1 E280A mutation, this study tests donanemab, RG6289, or both to see if the treatment can slow or alter disease progression.

  Recruiting Phase 2/3 Banner Health · Medellín, Antioquia · NCT06996730

• Comparing Donanemab with Usual Care for Early Alzheimer's Disease

  This study is testing if adding donanemab to regular care can help people with early Alzheimer's disease feel better over time compared to just sticking with usual care.

  Recruiting Eli Lilly and Company · Huntsville, Alabama · NCT06566170

Quick answers

How many clinical trials of Donanemab are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (3 trials), Japan (2 trials), Colombia (1 trial), China (1 trial), Puerto Rico (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 2/3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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