Condition

Node-positive Breast Cancer clinical trials and research

• 7Clinical trials
• 5Countries

Newest Node-positive Breast Cancer clinical trials

All recruiting trials (7)

• Preoperative chemotherapy with pembrolizumab and a low or high radiation boost for node-positive triple-negative breast cancer

  This study tests whether giving a low or high radiation boost together with preoperative chemotherapy and pembrolizumab can better activate the immune system in people with node‑positive triple‑negative breast cancer.

  Recruiting Phase 2 UNC Lineberger Comprehensive Cancer Center · Chapel Hill, North Carolina · NCT07276880

• Targeted sentinel node biopsy for breast cancer patients with limited axillary nodal disease

  This audit will test if removing the marked node along with the sentinel nodes can identify people with only 1–2 positive axillary nodes so some can avoid a full axillary dissection, for adults with cT1-2 breast cancer and biopsy-proven axillary metastases with no more than two abnormal nodes on imaging.

  Recruiting at 14 sites University Hospitals of Derby and Burton NHS Foundation Trust · Burnley and 13 other locations · NCT07085442

• Screening for metastasis in node-positive breast cancer after treatment

  This study is testing how often breast cancer spreads to other parts of the body in patients who have had chemotherapy and surgery, by using CT scans to check for any signs of metastasis.

  Recruiting Phase 2 H. Lee Moffitt Cancer Center and Research Institute · Tampa, Florida · NCT06833502

• Using 68Ga-FAPi-46 PET/CT to study breast cancer

  This study is testing a new imaging method using a special agent to see if it can help women with node-positive breast cancer get better information about their tumors before starting treatment.

  Recruiting European Institute of Oncology · Milan, Italy · NCT06790264

• Comparing two radiation therapies for node-positive breast cancer

  This study is testing if a new type of radiation therapy that gives higher doses in fewer sessions can help people with node-positive breast cancer just as well as the standard treatment, while also making their lives easier.

  Recruiting Phase 2 Washington University School of Medicine · St Louis, Missouri · NCT06559540

• Evaluating targeted axillary dissection in breast cancer with multiple suspicious lymph nodes

  This study is testing if a less invasive surgery called targeted axillary dissection can safely help patients with breast cancer who have multiple suspicious lymph nodes after they receive initial treatment.

  Recruiting Kliniken Essen-Mitte · Essen · NCT05462457

• Ovarian function suppression for premenopausal women with low-risk breast cancer

  This study is testing if lowering ovarian function with hormone treatments can help premenopausal women with low-risk breast cancer after surgery feel better and avoid chemotherapy.

  Recruiting Phase 4 Gangnam Severance Hospital · Seoul, Korea and 1 other locations · NCT05333328

Related topics

Quick answers

How many Node-positive Breast Cancer clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (3 trials), South Korea (1 trial), Italy (1 trial), Germany (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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