Condition

Neovascular Age-related Macular Degeneration clinical trials and research

• 11Clinical trials
• 33Countries

Newest Neovascular Age-related Macular Degeneration clinical trials

All recruiting trials (11)

• ABP 938 8 mg vs EYLEA® HD (aflibercept) in neovascular AMD

  This trial tests whether ABP 938 8 mg works as well as aflibercept 8 mg in people with neovascular AMD.

  Recruiting at 81 sites Phase 3 Amgen · Fullerton, California and 80 other locations · NCT07614776

• PRL3-zumab for neovascular (wet) age-related macular degeneration

  This trial tests whether three intravenous doses of PRL3-zumab given every two weeks can help people with neovascular (wet) age-related macular degeneration who have not responded to at least two standard intravitreal treatments.

  Recruiting Phase 1/2 Intra-IMMUSG Pte Ltd · Singapore · NCT07547228

• IBI302 treatment for neovascular age-related macular degeneration

  This trial will try intravitreal 8 mg IBI302 injections to see if they help people aged 50 and older with active neovascular (wet) AMD.

  Recruiting Phase 2 Innovent Biologics Technology Limited (Shanghai R&D Center) · Shanghai, Shanghai Municipality · NCT07275840

• LX111 gene therapy for neovascular (wet) age-related macular degeneration

  This will test a single eye injection of LX111 gene therapy in people 50 and older with active wet AMD to see if it is safe and helps maintain or improve vision.

  Recruiting Early Phase 1 Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · Shanghai · NCT07053358

• Surabgene Lomparvovec to reduce injections and preserve vision in adults with wet AMD

  This study will test whether a single subretinal dose of Surabgene Lomparvovec can reduce the need for repeated eye injections and help preserve vision in adults 50 and older with previously treated neovascular (wet) AMD compared with standard ranibizumab care.

  Recruiting at 138 sites Phase 3 AbbVie · Mesa, Arizona and 137 other locations · NCT07007065

• Effects of Faricimab on kidney function in diabetic patients

  This study is testing if a new eye injection called Faricimab can help improve kidney function in people with diabetes compared to a standard treatment.

  Recruiting University Hospital, Alexandroupolis · Alexandroupoli, Evros and 1 other locations · NCT06929507

• Port Delivery System with ranibizumab refilled every 36 weeks for neovascular (wet) AMD

  This trial tests whether a refillable eye implant that delivers ranibizumab every 36 weeks works and is safe for people with recent neovascular (wet) age-related macular degeneration who responded to prior anti-VEGF injections.

  Recruiting at 63 sites Phase 3 Hoffmann-La Roche · Innsbruck and 63 other locations · NCT06847542

• Gene therapy for wet age-related macular degeneration

  This study is testing a new gene therapy to see if it can help people with wet age-related macular degeneration keep their vision and reduce the need for frequent treatments.

  Recruiting Phase 1/2 Frontera Therapeutics · Tianjin, Tianjin,China · NCT06492863

• Gene therapy for neovascular age-related macular degeneration

  This study is testing a new gene therapy injection to see if it can safely improve vision in people with a specific type of age-related eye disease.

  Recruiting Phase 1/2 Shanghai Refreshgene Technology Co., Ltd. · Tianjin, Tianjin Municipality · NCT06141460

• Injection of SKG0106 for treating wet age-related macular degeneration

  This study is testing a new injection called SKG0106 to see if it can safely help people with wet age-related macular degeneration improve their vision.

  Recruiting at 8 sites Phase 1/2 Skyline Therapeutics · St. Petersburg, Florida and 8 other locations · NCT05986864

• Long-term evaluation of a delivery system for eye treatment in age-related macular degeneration

  This study is testing a new delivery system for eye treatment to see if it is safe and effective for people with a specific type of age-related vision loss.

  Recruiting at 71 sites Phase 3 Hoffmann-La Roche · Phoenix, Arizona and 164 other locations · NCT03683251

Related topics

Quick answers

How many Neovascular Age-related Macular Degeneration clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 33 countries. The most sites are in China (5 trials), Spain (4 trials), United States (4 trials), Czechia (3 trials), Austria (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 4, Phase 3: 4, Phase 2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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