Condition

Muscular Atrophy, Spinal clinical trials and research

• 5Clinical trials
• 13Countries

Newest Muscular Atrophy, Spinal clinical trials

All recruiting trials (5)

• Salanersen after early gene therapy in babies with SMA

  This study tests whether adding salanersen (BIIB115) after early gene therapy with Onasemnogene abeparvovec helps babies with SMA.

  Recruiting Phase 3 Biogen · Flower Mound, Texas · NCT07444450

• Salanersen given before symptoms to help movement in babies with genetic SMA

  This study will try salanersen in newborns with genetically confirmed SMA who have 2 or 3 copies of SMN2 to see if starting treatment before symptoms prevents or lessens movement problems.

  Recruiting at 14 sites Phase 3 Biogen · Chicago, Illinois and 13 other locations · NCT07221669

• Understanding how nusinersen is processed in the body using a new delivery system for spinal muscular atrophy

  This study is testing a new way to deliver the medication nusinersen for spinal muscular atrophy to see how it works in the body compared to the usual method.

  Recruiting at 19 sites Phase 1 Biogen · Phoenix, Arizona and 20 other locations · NCT06555419

• Evaluating pregnancy outcomes in women with spinal muscular atrophy exposed to Spinraza

  This study is trying to see how pregnancy goes for women with spinal muscular atrophy who have used Spinraza, compared to women without the condition who haven't used the drug.

  Recruiting at 13 sites Biogen · Palo Alto, California and 13 other locations · NCT05789758

• Observing the natural history of spinal muscular atrophy

  This study is trying to understand how spinal muscular atrophy affects patients over time by looking at their experiences and health data from both treated and untreated individuals.

  Recruiting at 5 sites Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Genova and 4 other locations · NCT05755451

Quick answers

How many Muscular Atrophy, Spinal clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in United States (4 trials), Italy (2 trials), United Kingdom (2 trials), Australia (1 trial), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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