Condition

Moderately to Severely Active Crohns Disease clinical trials and research

• 4Clinical trials
• 39Countries

Newest Moderately to Severely Active Crohns Disease clinical trials

All recruiting trials (4)

• Afimkibart for children with moderate to severe Crohn's disease

  This phase 3 trial tests Afimkibart to see if it helps children with moderately to severely active Crohn's disease while measuring safety.

  Recruiting at 19 sites Phase 3 Hoffmann-La Roche · New York, New York and 18 other locations · NCT07298421

• Evaluating a new treatment for active Crohn's disease

  This study is testing a new drug called RO7790121 to see if it can help people with moderate to severe Crohn's disease feel better when other treatments haven't worked.

  Recruiting at 198 sites Phase 3 Hoffmann-La Roche · Dothan, Alabama and 207 other locations · NCT06819891

• Evaluating a new treatment for active Crohn's disease

  This study is testing a new medication for people with moderately to severely active Crohn's disease to see if it helps them feel better compared to a placebo.

  Recruiting at 357 sites Phase 3 Hoffmann-La Roche · Dothan, Alabama and 374 other locations · NCT06819878

• Evaluating Transmural Healing in Crohn's Disease Treatment

  This study is testing if a new way of treating Crohn's disease that uses noninvasive ultrasound to track healing can help patients stay off corticosteroids and feel better compared to standard treatment.

  Recruiting at 51 sites Phase 4 Alimentiv Inc. · Los Angeles, California and 68 other locations · NCT06257706

Related topics

Quick answers

How many Moderately to Severely Active Crohns Disease clinical trials are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 39 countries. The most sites are in Australia (4 trials), Brazil (3 trials), United Kingdom (3 trials), United States (3 trials), Belgium (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 3, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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