Condition
Leptomeningeal Metastases clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Leptomeningeal Metastases clinical trials that are recruiting, at sites in 2 countries (most in China (2), United States (1)). By phase: Phase 1 (2), Phase 1/2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 2Countries
Newest Leptomeningeal Metastases clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Sacituzumab govitecan plus intrathecal pemetrexed for leptomeningeal metastases from HER2-negative breast cancer | Phase 1/2 | Huizhou, Guangdong | Recruiting | Jun 17, 2024 |
| Dual-targeting CAR-T therapy for advanced cancer patients with pleural or peritoneal metastases | Phase 1 | Chengdu, Sichuan | Recruiting | Jul 28, 2022 |
| Testing Deferoxamine for Leptomeningeal Metastasis Treatment | Phase 1 | Basking Ridge, New Jersey and 6 other locations | Recruiting | Jan 11, 2022 |
All recruiting trials (3)
-
Sacituzumab govitecan plus intrathecal pemetrexed for leptomeningeal metastases from HER2-negative breast cancer
This tests whether sacituzumab govitecan combined with intrathecal pemetrexed can help people with leptomeningeal metastases from HER2-negative breast cancer.
-
Dual-targeting CAR-T therapy for advanced cancer patients with pleural or peritoneal metastases
This study is testing a new type of CAR-T therapy that targets specific proteins in advanced cancer patients with tumors in the pleural or peritoneal cavities to see if it helps them when other treatments haven't worked.
-
Testing Deferoxamine for Leptomeningeal Metastasis Treatment
This study is testing if giving a drug called deferoxamine directly into the spinal fluid can safely help people with leptomeningeal metastasis from solid tumors.
Related topics
Quick answers
How many Leptomeningeal Metastases clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in China (2 trials), United States (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.