Condition
Indolent Systemic Mastocytosis clinical trials and research
As of November 12, 2026, Find a Trial lists 4 Indolent Systemic Mastocytosis clinical trials that are recruiting, at sites in 25 countries (most in United States (3), Germany (2), Argentina (1)). By phase: Phase 2/3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 25Countries
Newest Indolent Systemic Mastocytosis clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Real-world care and outcomes for people with indolent systemic mastocytosis (ISM) | — | Aurora, Colorado and 6 other locations | Recruiting | Dec 4, 2025 |
| Observing avapritinib treatment in people with indolent systemic mastocytosis in Germany | — | Berlin and 11 other locations | Recruiting | Dec 1, 2025 |
| Angioedema biomarker tests to help diagnose recurrent swelling | — | Wheaton, Maryland | Recruiting | Jan 18, 2024 |
| Evaluating BLU-263 for Indolent Systemic Mastocytosis | Phase 2/3 | Birmingham, Alabama and 87 other locations | Recruiting | Jun 2, 2021 |
All recruiting trials (4)
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Real-world care and outcomes for people with indolent systemic mastocytosis (ISM)
This study will see how people with ISM are treated and how they are doing in everyday care, including those taking avapritinib.
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Observing avapritinib treatment in people with indolent systemic mastocytosis in Germany
This study will see if avapritinib helps manage symptoms in people with indolent systemic mastocytosis who are starting the drug as part of routine care in Germany.
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Angioedema biomarker tests to help diagnose recurrent swelling
This study tests multiple blood-based diagnostic tests to see if they can better identify the cause of recurrent angioedema in patients compared with current tests.
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Evaluating BLU-263 for Indolent Systemic Mastocytosis
This study is testing if a new medication called elenestinib can help people with indolent systemic mastocytosis who aren't getting enough relief from their current treatments.
Related topics
Quick answers
How many Indolent Systemic Mastocytosis clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 25 countries. The most sites are in United States (3 trials), Germany (2 trials), Argentina (1 trial), Australia (1 trial), Austria (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.