Condition

High Risk clinical trials and research

• 5Clinical trials
• 3Countries

Newest High Risk clinical trials

All recruiting trials (5)

• Venetoclax plus azacitidine consolidation vs standard chemotherapy before stem cell transplant in high-risk AML

  This study tests whether a venetoclax-containing consolidation helps newly diagnosed high-risk AML patients who have CR/CRi after VA induction to improve outcomes before allo-HSCT.

  Recruiting Phase 2 The First Affiliated Hospital of Soochow University · Suzhou, Jiangsu · NCT07425782

• Home fetal heart and contraction monitoring for high-risk pregnancies

  This will test whether using a home fetal heart and contraction monitor once a week is practical and acceptable for women with certain high-risk singleton pregnancies from 32 weeks onward.

  Recruiting Birmingham Women's NHS Foundation Trust · Birmingham · NCT07124325

• Tonsil removal plus immunosuppression for high-risk IgA nephropathy in Caucasian adults

  This trial will see if removing the tonsils combined with immunosuppressive medicine helps Caucasian adults with high-risk IgA nephropathy preserve kidney function and reduce proteinuria.

  Recruiting at 2 sites St. Petersburg State Pavlov Medical University · Saint Petersburg and 1 other locations · NCT07074951

• Predicting bipolar disorder risk in children and teens with family history or atypical depression

  This project will try a prediction model to see if it can identify children and adolescents at high risk for bipolar disorder, including offspring of people with bipolar disorder and youths with atypical depression.

  Recruiting Shanghai Mental Health Center · Shanghai, Shanghai Municipality · NCT07031661

• MRD-guided treatment for high-risk newly diagnosed multiple myeloma

  This treatment will test whether combining daratumumab, carfilzomib, lenalidomide and dexamethasone, with or without autologous stem‑cell transplant and MRD‑guided maintenance, can keep high‑risk newly diagnosed multiple myeloma patients free of measurable disease for one year.

  Recruiting Phase 4 The First Affiliated Hospital of Soochow University · Suzhou, Jiangsu · NCT06409702

Related topics

Quick answers

How many High Risk clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in China (3 trials), Russia (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →