Condition
HAE clinical trials and research
As of November 12, 2026, Find a Trial lists 4 HAE clinical trials that are recruiting, at sites in 24 countries (most in United States (4), Argentina (2), Australia (2)). By phase: Phase 3 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 24Countries
Newest HAE clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Hemorrhoidal artery embolization versus rubber band ligation for internal hemorrhoid bleeding | — | Los Angeles, California | Recruiting | Apr 30, 2026 |
| Long-term treatment with ADX-324 for people with hereditary angioedema | Phase 3 | Litchfield Park, Arizona and 47 other locations | Recruiting | Feb 23, 2026 |
| Hemorrhoidal artery embolization to improve internal hemorrhoid symptoms | — | Los Angeles, California | Recruiting | Sep 18, 2025 |
| STOP-HAE: ADX-324 for hereditary angioedema | Phase 3 | Litchfield Park, Arizona and 69 other locations | Recruiting | May 7, 2025 |
All recruiting trials (4)
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Hemorrhoidal artery embolization versus rubber band ligation for internal hemorrhoid bleeding
This trial will test whether hemorrhoidal artery embolization or rubber band ligation better stops bleeding and improves symptoms in adults with internal hemorrhoids.
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Long-term treatment with ADX-324 for people with hereditary angioedema
This extension will try additional doses of ADX-324 (onvuzosiran) to see if continuing the drug is safe and helps people with Type I or II hereditary angioedema who finished the earlier Phase 3 trial.
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Hemorrhoidal artery embolization to improve internal hemorrhoid symptoms
This trial will try blocking enlarged hemorrhoidal arteries to reduce bleeding and other symptoms in adults with symptomatic internal hemorrhoids who cannot or will not have surgery.
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STOP-HAE: ADX-324 for hereditary angioedema
This trial tests whether ADX-324 can reduce HAE attacks in adults with Type 1 or Type 2 hereditary angioedema.
Related topics
Quick answers
How many HAE clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 24 countries. The most sites are in United States (4 trials), Argentina (2 trials), Australia (2 trials), Austria (2 trials), Belgium (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.