Condition
Empyema, Pleural clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Empyema, Pleural clinical trials that are recruiting, at sites in 2 countries (most in United States (2), Netherlands (1)). 1 was first registered in the last 30 days. By phase: Phase 4 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 1New in 30 days
- 2Countries
Newest Empyema, Pleural clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| VATS vs Intrapleural Enzymatic Therapy for Empyema in Adults | Phase 4 | Amsterdam | Recruiting | Oct 21, 2026 |
| Once-daily intrapleural enzyme treatment for complicated pleural infections | Phase 4 | Little Rock, Arkansas and 10 other locations | Recruiting | Jul 31, 2025 |
| Flushing chest drains to improve outcomes in pleural infections | — | Sterling Heights, Michigan and 4 other locations | Recruiting | May 24, 2024 |
All recruiting trials (3)
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VATS vs Intrapleural Enzymatic Therapy for Empyema in Adults
This trial tests whether VATS surgery or intrapleural enzymatic therapy helps adults with pleural infection (empyema) when standard treatment hasn’t worked.
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Once-daily intrapleural enzyme treatment for complicated pleural infections
This will see if giving tPA and DNase once a day through a chest tube works as well as giving them twice a day for people with complicated pleural infections.
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Flushing chest drains to improve outcomes in pleural infections
This study is testing if flushing chest drains with saline every six hours can help people with serious lung infections recover faster and spend less time in the hospital.
Related topics
Quick answers
How many Empyema, Pleural clinical trials are recruiting right now?
3, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (2 trials), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.