Condition
Early Onset Alzheimer Disease clinical trials and research
Research outlook What's coming for Alzheimer's disease: the next 6 months to 5 yearsAs of November 12, 2026, Find a Trial lists 2 Early Onset Alzheimer Disease clinical trials that are recruiting, at sites in 5 countries (most in Colombia (1), Canada (1), Netherlands (1)). By phase: Phase 2/3 (1), Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 2Clinical trials
- 5Countries
All recruiting trials (2)
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Donanemab and RG6289 in PSEN1 E280A Mutation Carriers with autosomal-dominant Alzheimer’s disease
Aimed at people with the PSEN1 E280A mutation, this study tests donanemab, RG6289, or both to see if the treatment can slow or alter disease progression.
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Evaluating ALN-APP for Early-Onset Alzheimer's Disease
This study is testing a new treatment called ALN-APP to see if it is safe and can help people with early-onset Alzheimer's disease.
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Quick answers
How many Early Onset Alzheimer Disease clinical trials are recruiting right now?
2, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 5 countries. The most sites are in Colombia (1 trial), Canada (1 trial), Netherlands (1 trial), United Kingdom (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2/3: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.