Condition

Colorectal Cancer Liver Metastases (CRLM) clinical trials and research

• 5Clinical trials
• 1New in 30 days
• 10Countries

Newest Colorectal Cancer Liver Metastases (CRLM) clinical trials

All recruiting trials (5)

• ctDNA methylation-guided adjuvant therapy after removing colorectal liver metastases

  This trial tests whether using a blood test that detects ctDNA methylation after surgery can guide adjuvant therapy for patients who had colorectal cancer spread to the liver and were operated on with no remaining disease.

  Recruiting Phase 2 Fudan University · Shanghai, Shanghai Municipality · NCT07917104

• AK104 plus radiotherapy with standard first-line treatment for pMMR/MSS colorectal cancer liver metastases

  This trial will test whether adding AK104 and targeted liver radiotherapy to standard first-line therapy helps people with pMMR/MSS colorectal cancer that has spread to the liver.

  Recruiting Phase 2 Fudan University · Shanghai · NCT07544784

• AI-based prediction of liver metastasis after colorectal cancer surgery

  This project will try a deep learning model that combines CT scans, digitized pathology slides, and routine clinical data to predict which stage I–III colorectal cancer patients are likely to develop liver metastases after curative surgery.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT07399236

• Blood test using exosome microRNAs to find extrahepatic spread in colorectal cancer with liver metastases

  This project will test whether a blood test measuring exosome microRNAs can detect extrahepatic metastases in adults whose colorectal cancer has spread to the liver.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07224724

• Comparing two methods to induce liver regeneration in colorectal cancer patients

  This study is testing if a new method that combines two types of vein blockage can help colorectal cancer patients with liver issues regenerate their liver better than the standard method.

  Recruiting at 20 sites Maastricht University · New Haven, Connecticut and 23 other locations · NCT05428735

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Quick answers

How many Colorectal Cancer Liver Metastases (CRLM) clinical trials are recruiting right now?

5, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in China (3 trials), United States (2 trials), Australia (1 trial), Austria (1 trial), Belgium (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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