Condition
Articular Cartilage Defect clinical trials and research
As of November 12, 2026, Find a Trial lists 6 Articular Cartilage Defect clinical trials that are recruiting, at sites in 4 countries (most in United States (3), Canada (1), China (1)). By phase: Phase 3 (2), Phase 1 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 6Clinical trials
- 4Countries
Newest Articular Cartilage Defect clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| MACI versus bone marrow stimulation for symptomatic ankle cartilage defects in people 17–65 | Phase 3 | Gilbert, Arizona and 11 other locations | Recruiting | Apr 8, 2025 |
| Using rib cartilage to treat ankle joint lesions | — | Guangzhou, Guangdong | Recruiting | Jul 12, 2023 |
| Comparing AMIC and microfracture for hip cartilage damage | Phase 1 | Hamilton, Ontario | Recruiting | Jun 2, 2022 |
| Evaluating CartiLife® for knee cartilage defects | Phase 2 | Irvine, California and 4 other locations | Recruiting | Feb 9, 2021 |
| Using autologous chondrocyte suspension for knee cartilage repair | — | Lausanne, Canton of Vaud | Recruiting | Mar 5, 2020 |
| Comparing MACI and microfracture treatments for knee cartilage defects in teens | Phase 3 | Palo Alto, California and 14 other locations | Recruiting | Jul 17, 2018 |
All recruiting trials (6)
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MACI versus bone marrow stimulation for symptomatic ankle cartilage defects in people 17–65
This treatment comparison tests whether MACI (your own cultured cartilage cells on a collagen membrane) works better than bone marrow stimulation for people aged 17 to 65 with symptomatic cartilage defects of the talus.
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Using rib cartilage to treat ankle joint lesions
This study is testing whether using rib cartilage to treat ankle joint damage can help people recover better and have fewer side effects than a different treatment.
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Comparing AMIC and microfracture for hip cartilage damage
This study is testing whether a new treatment called AMIC works better than microfracture for helping people with hip cartilage damage feel better and improve their quality of life after surgery.
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Evaluating CartiLife® for knee cartilage defects
This study is testing if a new treatment using patients' own cartilage cells can help adults with knee cartilage damage feel better and improve their knee function.
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Using autologous chondrocyte suspension for knee cartilage repair
This study is testing whether using a patient’s own cartilage cells can help repair knee cartilage damage and improve their knee function over a year.
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Comparing MACI and microfracture treatments for knee cartilage defects in teens
This study is testing whether a new cartilage treatment called MACI works better than a standard procedure called microfracture for knee problems in teens aged 10 to 17.
Related topics
Quick answers
How many Articular Cartilage Defect clinical trials are recruiting right now?
6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in United States (3 trials), Canada (1 trial), China (1 trial), Switzerland (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 2, Phase 1: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.