Zirconia versus titanium abutments for single posterior implant restorations

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled clinical trial compares prefabricated titanium abutments with customized milled zirconia abutments in adults receiving single implant-supported posterior zirconia crowns after prior alveolar preservation and implant placement. After implant osseointegration, eligible participants from the earlier alveolar-preservation trial are randomly assigned 1:1 to receive either the standardized titanium abutment (TiB) or the customized anatomical zirconia abutment (ZiT), with all prosthetic and laboratory procedures standardized. Clinical and radiographic assessments target peri-implant soft tissues, implant biocompatibility, bone-level changes, and oral-health related quality of life at prosthesis delivery (baseline) and scheduled follow-up visits. Sample size was calculated with GPower and allocation is computer-generated to ensure adequate statistical power and concealment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Individuals aged 18 years or older;
2. Participants in the Master's Thesis entitled: "Dimensional Changes Following Different Alveolar Preservation Protocols in Posterior Regions: A Randomized Controlled Study";
3. Patients with implants and healing abutments from Bionnovation Biomedical in place at the time of prosthetic rehabilitation;
4. Implants without surrounding bone loss;
5. Signed informed consent form.

Exclusion Criteria:

1. Patients with uncontrolled systemic diseases;
2. Pregnant or lactating women;
3. Smokers or former smokers;
4. Undergoing orthodontic treatment;
5. Using medications that interfere with bone healing, such as those for osteoporosis and bisphosphonates;
6. Implants with bone loss or failed implants.

Where it's running

• Piracicaba Dental School
  Piracicaba, São Paulo, Brazil Recruiting

Study contacts

• Principal investigator: Renato Casarin, Associate Professor — University of Campinas, Brazil
• Study coordinator: Leticia Sandoli Arroteia, Ms and PhD Student
• Email: leticia.sandoli@hotmail.com
• Phone: +5514981600821

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.