Zinc oxide vs MEBO for stage 2 pressure ulcers

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with newly diagnosed stage 2 pressure ulcers at King Abdullah Medical City are randomized 1:1 to receive either topical zinc oxide or MEBO ointment. Treatments are applied twice every 12 hours and patients are examined daily until complete healing or for up to one month. Wound healing is measured using the Bates-Jensen Wound Assessment Tool and data are recorded on a standardized assessment sheet. Randomization is performed electronically in R using the Random Allocation Rule.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Willing to participate.
* KAMC cases in medical ward, neuroscience ward, and intensive care unit.
* Newly cases diagnosed with second stage pressure ulcer according to the European pressure ulcer advisory panel/national pressure ulcer advisory panel (NPUAP) guidelines.

Exclusion Criteria:

* Not consenting to participate
* Patients with suspected hypersensitivity reactions to any of the topical formulation's ingredients.
* Either a category III or IV pressure ulcer.
* Evidence of deep tissue injury (exudative drainage, purple or maroon localized area of discolored intact skin or blood-filled blister due to pressure damage).
* Signs of wound infection (pus draining from the ulcer, a foul-smelling odour, tenderness, heat and increased redness in the surrounding skin and fever).
* Patients who undertaking other therapies that could affect healing, such as corticosteroids, radiation therapy, or chemotherapy for cancer.
* Heavy smoking (more than 20 cigarettes a day).
* Concomitant chronic disease (e.g., diabetes mellitus or frank vascular disease such as Buerger's disease).
* Patients who unable to continue the study because of death, discharge, or change in the care setting.

Where it's running

• King Abdulla Medical City in Holy capital
  Mecca, Western Reagan, Saudi Arabia Recruiting
• King Abdulla Medical City in Holy capital
  Mecca, Western Reagan, Saudi Arabia Completed

Study contacts

• Principal investigator: Dr. Ebtisam AbdElatif Ebrahim, Master degree of science in nu — King Abdullah Medical City in Holy Capital
• Study coordinator: wedian Almowallad, Master
• Email: Almwlld.W@kamc.med.sa
• Phone: +96612 5549999

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.