Yupingfeng Powder for Allergic Rhinitis in Adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional trial investigates the effects of Chinese Herbal Medicine granules (Yupingfeng Powder) versus placebo for adults with allergic rhinitis. It targets patients characterized by lung and spleen qi deficiency and who have multiple symptoms such as runny nose, sneezing, nasal obstruction, or itching for at least one hour daily. The study combines Phase 2 and Phase 3 to evaluate safety and efficacy, using a randomized, blinded design typical of clinical evaluations. Primary outcomes likely include symptom improvement and quality of life, with secondary outcomes addressing safety and tolerability. This trial is conducted at the Hong Kong Institute of Integrative Medicine and is sponsored by The Chinese University of Hong Kong.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 18 or above;
* Subjects with deficiency of lung and spleen Qi;
* At least 2 or more allergic symptoms (rhinorrhea, sneezing, nasal obstruction and nasal itching) for a cumulative period greater than 1 hour per day;
* Understand Chinese;
* Voluntary written consent.

Exclusion Criteria:

* Known chronic disease such as asthma, rhinosinusitis, nasal polyposis;
* Known severe medical conditions, such as cardiovascular, liver or renal dysfunction, diabetes mellitus, cancers, cerebrovascular diseases, blood system diseases;
* Concomitant steroid, nonsteroidal anti-inflammatory drugs (NSAIDs), anticoagulant, and immunotherapy within past month;
* Impaired hematological profile and liver / renal function exceeds the upper limit of the reference value by 2 times ;
* Known alcohol and / or drug abuse;
* Known allergic history to any Chinese herbal medicines;
* Known pregnant or lactating.

Where it's running

• Hong Kong Institute of Integrative Medicine
  Shatin, Hong Kong Recruiting

Study contacts

• Principal investigator: Zhixiu Lin, PhD — Chinese University of Hong Kong
• Study coordinator: Zhixiu LIN, PhD
• Email: linzx@cuhk.edu.hk
• Phone: +85235053476

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Mannan-Conjugated Allergoids for House Dust M mite Allergy

  A new treatment named EP-088_MM09 is being tested to see if it can reduce nasal and eye allergy symptoms (and possibly asthma) in people aged 12 to 65 who are allergic to house dust mites, compared with a placebo.

  Recruiting at 2 sites Phase 3 Inmunotek S.L. · Covilha, Castelo Branco District and 15 other locations · NCT07904195

• Mannan-conjugated Allergoids for House Dust Mite Allergy

  A new treatment called EP-088_MM09 is being tested to see if it can reduce allergy symptoms in people with house dust mite–related nasal allergy, with or without mild asthma.

  Recruiting at 4 sites Phase 3 Inmunotek S.L. · Coimbra and 15 other locations · NCT07904052

• Dog-allergy immunotherapy with Alutard SQ Dog in Swedish practice

  This study tests whether Alutard SQ Dog immunotherapy helps adults with moderate-to-severe dog allergy when used in real-world Swedish care.

  Recruiting at 2 sites Phase 4 Karolinska Institutet · Lund, Skåne County and 1 other locations · NCT07651891

• PL-14 Allergy Blocker vs saline spray for seasonal nasal allergies

  This study tests whether PL-14 Allergy Blocker, a drug-free nasal gel, reduces nasal allergy symptoms in adults with seasonal allergic rhinitis compared with saline spray.

  Recruiting at 4 sites Polyrizon Ltd. · Normal, Illinois and 4 other locations · NCT07588672

• Helping decide between nasal surgery options for chronic hypertrophic rhinitis

  A randomized trial will see if a printed patient decision aid helps adults with chronic hypertrophic rhinitis choose between surgical options more confidently and with less regret.

  Recruiting Taipei Medical University Shuang Ho Hospital · New Taipei City · NCT07435714

• Digital app to improve adherence to aeroallergen immunotherapy

  This project will test whether a smartphone app can help people with allergic rhinitis keep taking their prescribed aeroallergen immunotherapy for the full treatment course.

  Recruiting Fundación de Investigación Biomédica - Hospital Universitario de La Princesa · Madrid, Madrid · NCT07419230

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.