Yoga treatment for major depression

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional trial evaluates the effectiveness of yoga monotherapy over 12 weeks in adults with mild-to-moderate major depression. Participants will be randomly assigned to one of three groups: standard yoga practice, Ayurvedic yoga practice, or an educational control intervention. The primary outcome will be measured using the Beck Depression Inventory-II, while secondary outcomes will assess perceived stress and various biomarkers associated with depression. The study aims to determine if yoga can significantly reduce depression severity compared to the control group.

Why it matters

Who can join: the full rules

Inclusion criteria:

* 18 years of age or older
* Able to give voluntary, informed consent
* English-speaking
* Diagnosis of clinical depression

Exclusion criteria:

* Current use of antidepressant medication
* Current engagement in psychotherapy
* Current pregnancy
* Significant medical issues interfering with yoga practice

Where it's running

• Zuckerberg San Francisco General Hospital
  San Francisco, California, United States Recruiting

Study contacts

• Principal investigator: Sudha Prathikanti, MD — University of California, San Francisco
• Study coordinator: Sudha Prathikanti, MD
• Email: sudha.prathikanti@ucsf.edu
• Phone: 415-516-3867

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.