Xinqiao High-risk Diabetes Cohort (NICE)
Official title: Xinqiao High-risk Cohort of Diabetes
Run by Shanghai General Hospital, China · NCT07281170 · Data updated 2026-11-12
This project will screen adults in Xinqiao who are at high risk for diabetes or have prediabetes and use continuous glucose monitoring and health checks to track blood sugar patterns, eye and bone health, and see who progresses to diabetes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Months to 79 Years |
| Sex | All |
| Enrollment | 7000 (estimated) |
| Sponsor | Shanghai General Hospital, China Academic / other |
| Locations | 2 sites (Shanghai, Shanghai Municipality and 1 other locations) |
| Status | Recruiting |
| Started | October 8, 2019 |
| Main results expected | October 20, 2034 |
| Study ends | December 31, 2034 |
| Registry record updated | July 29, 2026 |
| Trial ID | NCT07281170 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18) living in the Xinqiao/Songjiang area who have a smartphone and a family history of diabetes or a prior abnormal glucose test are ideal candidates.
✕Probably not a fit
People already diagnosed with diabetes, those with recent surgery, acute cardiovascular events, active infections, other conditions judged unsafe for participation, or without a smartphone or ability to attend hospital visits are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The project will create a standardized cohort of adults in the Xinqiao/Songjiang area identified as high-risk for diabetes or with prediabetes through community screening. Participants will use continuous glucose monitoring (CGM) and undergo ophthalmology and bone density exams, with clinical and lifestyle data collected at baseline and during follow-up. Investigators will track annual conversion rates from prediabetes to diabetes, characterize early changes in glucose metabolism and pancreatic islet function, and document glycemic variability. The goal is to identify high-risk patterns and effective interventions and to develop a practical local management model for high-risk patients.
Why it matters
Potential benefit: If successful, this project could identify people most likely to develop diabetes early and enable targeted actions to prevent or delay disease onset.
How similar studies have gone: Previous cohort and CGM-based research has shown that monitoring glucose patterns can reveal early dysglycemia and predict progression, but applying these methods as a local community management model is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals who provide written informed consen * Have access to a smartphone * Hamily history of diabetes or abnormal microglucose level detected once * Age ≥18 years at the time of consent Exclusion Criteria: * Diabetes mellitus * Any other condition which, in the judgment of the investigator, would make the subject unsuitable for enrollment in the study * recently surgical histories, trauma, acute cardiovascular complications, or infectious diseases
Where it's running
-
Shanghai General Hospital
Shanghai, Shanghai Municipality, China Recruiting -
Shanghai 6th People's Hospital
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Study coordinator: Li Wen
- Email: li_winfield@foxmail.com
- Phone: +8618701835861
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.