Work-related sun exposure and skin melanoma in the Modena area
Official title: Melanoma of the Skin and Exposure to Solar Ultraviolet Radiation at Work in Modena Territory: a Case-control Study to Promote an Active Search and Prevention of Occupational Diseases Based on Recent INAIL Criteria
Run by University of Modena and Reggio Emilia · NCT07251335 · Data updated 2026-11-12
This project will see if people who work outdoors in the Modena area are more likely to develop types of melanoma linked to long-term sun exposure.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | University of Modena and Reggio Emilia Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Modena, Mo) |
| Status | Recruiting |
| Started | July 7, 2025 |
| Main results expected | April 2027 |
| Study ends | November 2027 |
| Registry record updated | December 18, 2025 |
| Trial ID | NCT07251335 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) who are patients at the Modena University Hospital Dermatology Clinic undergoing biopsy for a suspected skin lesion and able to give informed consent in Italian.
✕Probably not a fit
People under 18, patients with cognitive impairments that prevent reliable interviews, or people not treated at the Modena clinic are not eligible and unlikely to benefit directly.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a monocentric, observational case-control project at the Dermatology Clinic of the University Hospital of Modena that enrolls adults undergoing skin biopsy for a suspected melanoma. Participants complete a one-time interview about job history, specific work locations, and sun exposure habits to estimate lifetime occupational and recreational UV radiation exposure. Researchers will classify melanoma subtypes by cumulative solar damage and apply recent INAIL criteria to determine whether certain melanomas can be reported as occupational diseases. The study aims to clarify the link between long-term outdoor work and CSD-associated melanomas and to inform prevention and reporting practices for outdoor workers.
Why it matters
Potential benefit: If successful, findings could help identify melanomas caused by long-term occupational sun exposure, improve reporting for workers' compensation, and guide prevention efforts for outdoor workers.
How similar studies have gone: Previous studies and a WHO/ILO meta-analysis found an increased risk of cumulative-sun-damage-related melanoma with outdoor work but overall evidence is mixed, and applying recent INAIL criteria in this local population is a relatively new approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Be a patient of the Dermatology Clinic at the University Hospital of Modena. * Be 18 years of age or older. * Have undergone a dermatological screening for a suspected skin lesion. * Be able to understand and sign an informed consent form in italian language. Exclusion Criteria: * Be under 18 years of age. * Have cognitive impairment that prevents providing reliable answers to the interview or recalling past exposures.
Where it's running
-
Dipartimento di Scienze Biomediche, Metaboliche e Neuroscienze
Modena, Mo, Italy Recruiting
Study contacts
- Principal investigator: Alberto Modenese, MD. PhD — University of Modena and Reggio Emilia
- Study coordinator: Alberto Modenese, MD, PhD
- Email: alberto.modenese@unimore.it
- Phone: +39 059 205 5461
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.