Whole-body light therapy for motor and thinking symptoms in Parkinson's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center interventional study gives ambulatory adults with Parkinson's disease whole-body photobiomodulation sessions lasting 20 minutes, roughly three times per week, for about 10 weeks. Participants will be monitored before, during, and after treatment for changes in motor function, cognitive performance, and safety outcomes. Eligibility focuses on Hoehn and Yahr stages 1–3 and age 40 or older, and excludes those with severe cognitive impairment, implanted electronic devices, seizures, or major psychiatric conditions. The trial is exploratory and aims to characterize the magnitude and tolerability of any motor or cognitive changes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Individuals diagnosed with Parkinson's disease at Hoehn and Yahr stages 1-3 based on medical history and examination
* Adults aged 40 years or older
* Individuals able to walk independently

Exclusion Criteria:

* Individuals with severe cognitive impairment (Korean Mini-Mental State Examination \[K-MMSE\] score ≤ 9) making it difficult to understand and perform tasks
* Patients with dementia other than Parkinson's disease dementia
* Individuals with implanted medical or other electronic devices
* Individuals with severe neuropsychiatric disorders
* Individuals treated for alcohol dependence within 6 months prior to screening
* Individuals with a history of suicide attempts
* Individuals with a history of seizures
* Individuals experiencing dyspnea while sitting at rest
* Individuals with visual impairment preventing them from reading ordinary text even with corrective lenses
* Individuals with hearing impairment preventing them from understanding conversation even with a hearing aid
* Individuals who have participated in two or more clinical trials in the same year or in another clinical trial within the past 6 months
* Women and men of childbearing potential who are planning pregnancy during the trial or who do not agree to use appropriate contraceptive methods
* Pregnant or breastfeeding women
* Individuals deemed medically inappropriate for participation by the principal investigator or study staff based on clinically significant findings not otherwise specified above

Where it's running

• Pusan National University Yangsan Hospital
  Yangsan, Gyeongsangnam-do, South Korea Recruiting

Study contacts

• Study coordinator: Jisoo Baik
• Email: zisoo@pusan.ac.kr
• Phone: 082+055-360-4159

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.