Who benefits from platelet-rich plasma injections for tennis elbow
Identification of Responders to Platelet-Rich Plasma (PRP) Injections in Lateral Elbow Epicondylalgia
This project tests whether platelet-rich plasma injections help adults with chronic tennis elbow and whether we can predict who will get better within 90 days.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 139 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape Academic / other |
| Locations | 1 site (Ploemeur) |
| Trial ID | NCT07496983 on ClinicalTrials.gov |
What this trial studies
This is an observational cohort of about 139 adults with chronic lateral epicondylalgia who received a PRP injection within the prior 48 hours. Participants attend baseline, Day 45, and Day 90 visits for clinical exams, pain ratings, grip strength, and functional outcome measures. The primary question is the proportion of patients who respond by 90 days, with secondary aims to link clinical, demographic, and occupational factors to response and to build a predictive model. Outcomes in responders and non-responders will be compared over the 90-day follow-up to characterize symptom and strength trajectories.
Who should consider this trial
Good fit: Adults aged 18 or older with clinically or imaging-diagnosed chronic lateral epicondylalgia lasting more than three months who received a PRP injection within the last 48 hours, are medically stable, and can consent are ideal candidates.
Not a fit: People who did not receive a PRP injection within 48 hours, have had symptoms for less than three months, are pregnant, under legal protection, or currently excluded by participation in another study are unlikely to benefit from this project.
Why it matters
Potential benefit: If successful, the results could help doctors target PRP injections to patients most likely to improve and avoid unnecessary procedures for others.
How similar studies have performed: Previous randomized and observational studies of PRP for tennis elbow have produced mixed results, so efforts to identify responders and predictive factors are common but not yet conclusive.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Chronic lateral epicondylalgia (tennis elbow), diagnosed clinically or by imaging (ultrasound or MRI), evolving for more than 3 months * PRP injection received within the last 48 hours * Medically stable * Able to provide informed consent/non-opposition * Affiliation to a social security system Exclusion Criteria: * PRP injection received more than 48 hours before inclusion * Participation in another clinical study with exclusion period * Adults under legal protection * Pregnant women
Where this trial is running
Ploemeur
- Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles (CMRRF) de Kerpape — Ploemeur, France (Recruiting)
Study contacts
- Study coordinator: Thomas Julienne, MD
- Email: thomas.julienne@vyv3.fr
- Phone: +33 2 97 82 60 27
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.