White noise to reduce infants' crying during blood draws and IV placement
The Effect of White Noise on Crying Duration After Invasive Procedures in Infants Aged 1-3 Months
This trial tests whether playing white noise during routine blood draws or IV placement helps calm 1–3 month-old, full-term infants and reduce crying and pain.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 37 (estimated) |
| Ages | 1 Month to 3 Months |
| Sex | All |
| Sponsor | Başakşehir Çam & Sakura City Hospital Government |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT07453641 on ClinicalTrials.gov |
What this trial studies
Term infants aged 1–3 months admitted to the general pediatric ward who are scheduled for routine invasive procedures such as venipuncture or intravenous line placement will receive white noise played during the procedure. Investigators will measure outcomes including crying duration, observable pain scores, and basic physical parameters before, during, and after the procedure. Infants with congenital anomalies, hearing impairments, prior analgesic use, or those requiring ICU monitoring are excluded. The intervention is non-pharmacological, has no known side effects, and is applied in a hospital setting in Istanbul.
Who should consider this trial
Good fit: Term infants aged 1–3 months admitted to the general pediatric ward and scheduled for routine venipuncture or IV placement who have no hearing impairment or congenital anomalies and have not received analgesics beforehand are ideal candidates.
Not a fit: Infants with hearing impairments, congenital anomalies, those already given pain medication before the procedure, or infants requiring ICU-level care are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, white noise could offer a simple, low-cost way to reduce pain, crying, and stress in young infants during routine procedures.
How similar studies have performed: Prior small studies and nonpharmacologic research suggest white noise can soothe infants and shorten crying, but robust randomized data for invasive procedures are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Infants aged 1-3 months * Born at term (≥37 weeks gestational age) * Admitted to the general pediatric ward * Scheduled for routine invasive procedures such as venipuncture or intravenous line placement Exclusion Criteria: * Infants with congenital anomalies * Infants with hearing impairments * Infants with a history of analgesic or pain-relieving medication use prior to the invasive procedure * Infants requiring intensive care unit (ICU) monitoring
Where this trial is running
Istanbul
- Basaksehir Cam ve Sakura City Hospital — Istanbul, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Esin YILDIZ ALDEMİR, MD, PhD
- Email: aldemiresin@gmail.com
- Phone: +905324859556
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.