What teens (11–17) and their parents think about hormone replacement for female hypogonadism

Current Knowledge and Perceptions of Hormone Replacement Therapy Among Patients Aged 11 to 18 Years, and Their Parents, Treated for Hypogonadism at the Strasbourg University Hospital

University Hospital, Strasbourg, France · NCT07315932

We will ask girls aged 11–17 with hypogonadism and their parents about their knowledge and feelings on hormone replacement therapy to see what education helps them stick with treatment.

Quick facts

Study typeObservational
Enrollment20 (estimated)
Ages11 Years to 18 Years
SexFemale
SponsorUniversity Hospital, Strasbourg, France (other)
Locations1 site (Strasbourg)
Trial IDNCT07315932 on ClinicalTrials.gov

What this trial studies

This observational project recruits female patients aged 11–17 treated at the University Hospital of Strasbourg for central or peripheral hypogonadism who have started hormone replacement therapy. Patients and their parents complete questionnaires and/or interviews about knowledge, beliefs, barriers, and practical challenges related to HRT. Responses are analyzed to identify common gaps and educational needs. The results will inform the design of therapeutic education workshops to improve understanding and adherence; no experimental treatments are administered.

Who should consider this trial

Good fit: Ideal candidates are girls aged 11–17 treated at CHU Strasbourg for central or peripheral hypogonadism who have recently started hormone replacement therapy and whose parents can participate.

Not a fit: Patients who cannot understand the study information (because of language barriers, illiteracy, or cognitive difficulties) or those treated outside the recruiting center are unlikely to benefit from this single-center effort.

Why it matters

Potential benefit: If successful, the project could improve patient and parent understanding of HRT and increase adherence, potentially improving clinical outcomes.

How similar studies have performed: Educational interventions in other pediatric endocrine and chronic conditions have improved adherence, but specific data on adolescent perceptions of HRT are limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Female patients aged 11 to 18 years
* Treated at the University Hospital of Strasbourg for central or peripheral hypogonadism with the initiation of hormone replacement therapy

Exclusion Criteria:

\- Inability to provide the subject with clear information (difficulties understanding the subject, language barrier, illiteracy, etc.)

Where this trial is running

Strasbourg

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Female Hypogonadism, Central hypogonadism, Peripheral hypogonadism, hormone replacement therapy

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.