What percentage of meniscus regrows after partial meniscectomy measured by high-resolution MRI
Official title: Assessment of the Degree of Regeneration After Partial Meniscectomy Based on Thin-layer MRI Image Segmentation and Reconstruction
Run by Beijing Tsinghua Chang Gung Hospital · NCT07885943 · Data updated 2026-11-12
This study tests how much meniscus tissue regrows at 6 and 12 months after partial meniscectomy using thin-slice MRI and 3D reconstruction.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | Beijing Tsinghua Chang Gung Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | January 1, 2024 |
| Main results expected | January 1, 2028 |
| Study ends | January 1, 2028 |
| Registry record updated | October 21, 2026 |
| Trial ID | NCT07885943 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults who had partial meniscectomy performed arthroscopically and have follow-up thin-slice MRI within one week after surgery, with no infections or other knee diseases.
✕Probably not a fit
Patients with contraindications to MRI, lack of post-surgical MRI within the specified window, or with unrelated knee conditions may derive no direct benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will use high-resolution thin-slice MRI and 3D reconstruction to quantify meniscus regeneration in patients who had partial meniscectomy. The study is a bi-directional, single-center cohort without an intervention, following patients at 6 and 12 months post-surgery. It also looks at how regeneration relates to factors like age, excision extent and location, and osteoarthritis, as well as knee function scores. Data come from retrospective follow-up and precise segmentation of imaging data with statistical analysis. The aim is to understand what influences regeneration and how it correlates with functional outcomes.
Why it matters
Potential benefit: If successful, findings could help predict which patients are more likely to experience meaningful meniscal regeneration after surgery.
How similar studies have gone: Prior research using imaging-based quantification has shown measurable regeneration in some patients, but this approach in a bi-directional cohort is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who underwent partial resection of the meniscus using arthroscopy in our hospital and had follow-up thin-slice MRI scans within one week after surgery; no cases of joint infection, joint tumors, or other diseases were present. Exclusion Criteria: * Patients who did not undergo an MRI scan within one week after surgery for the removal of the inferior meniscus using arthroscopy, who had MRI scan contraindications or refused the procedure. Patients who underwent nuclear magnetic resonance (NMR) re-evaluation and had undergone surgery at least half a year prior to the commencement of this experiment.
Where it's running
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Tsinghua Changgung Hospital, Beijing
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Study coordinator: Jiwen LONG
- Email: 1363477686@qq.com
- Phone: +86 13975982156
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.