What factors relate to testosterone levels in middle-aged men
Official title: Anthropometric, Functional and Lifestyle-related Factors Associated With Testosterone Levels Among Middle-aged Men in Uzbekistan: Protocol for a Population-based Cross-sectional Study
Run by Andijan State Medical Institute · NCT07476222 · Data updated 2026-11-12
Researchers will see if body size, fitness, and lifestyle factors are linked to total testosterone levels in about 600 men aged 35-59 in Andijan, Uzbekistan.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 35 Years to 59 Years |
| Sex | Men only |
| Enrollment | 600 (estimated) |
| Sponsor | Andijan State Medical Institute Academic / other |
| Locations | 1 site (Andijan) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | August 25, 2026 |
| Trial ID | NCT07476222 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are men aged 35-59 who live in the Andijan region, are willing to undergo assessments, and have no current testosterone therapy or major exclusion conditions listed.
✕Probably not a fit
Individuals with existing hypogonadism requiring treatment or those with severe comorbidities may see no direct benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a population-based cross-sectional study that looks at how anthropometric measurements, functional performance, and lifestyle factors relate to serum total testosterone in middle-aged men. Participants will undergo measurements such as BMI and waist size, performance tests, standardized questionnaires, and a blood test for testosterone. The aim is to identify modifiable factors that correlate with lower testosterone to inform preventive health strategies. The study is led by Andijan State Medical Institute with collaboration from Uzbek partners and will recruit men who reside in the Andijan region. Results could help in recognizing at-risk individuals earlier and guiding lifestyle interventions.
Why it matters
Potential benefit: If successful, the study could help identify modifiable factors associated with low testosterone, enabling earlier prevention and targeted lifestyle recommendations.
How similar studies have gone: Previous cross-sectional studies have found associations between obesity, activity, and testosterone, suggesting this approach can reveal meaningful relationships, though population context varies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men aged 35-59 years * Permanent residence in the Andijan region of Uzbekistan * Ability and willingness to provide written informed consent * Willingness to undergo clinical, anthropometric, functional and laboratory assessments Exclusion Criteria: * Previously diagnosed hypogonadism requiring testosterone replacement therapy * Current use of testosterone preparations or other medications known to substantially affect androgen status * Severe cardiovascular, hepatic or renal disease in the stage of decompensation * Clinically significant urological pathology * Severe psychiatric illness or cognitive impairment limiting study participation * Acute infectious or inflammatory conditions at the time of assessment
Where it's running
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Andijan State Medical Institute
Andijan, Uzbekistan Recruiting
Study contacts
- Principal investigator: Abdukhalim Kh. Abdurakhimov, PhD — Andijan State Medical Institute
- Study coordinator: Abdukhalim Kh. Abdurakhimov, PhD
- Email: abduhalim@adti.uz
- Phone: +998941010091
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.