What factors affect pregnancy success after IUI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a retrospective analysis of approximately 3,000 intrauterine insemination (IUI) cycles performed at the Chinese University of Hong Kong using existing clinical records. The study examines hormone measurements (LH, estradiol, progesterone) on trigger day, follicular response, endometrial thickness, and sperm parameters as predictors of clinical pregnancy (gestational sac with fetal heartbeat). Statistical methods include univariate and multivariate logistic regression, mediation and interaction analyses, ROC/AUC performance, and machine-learning model development with internal validation. The protocol also compares natural versus gonadotropin-stimulated IUI cycles and examines incremental cost per clinical pregnancy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Couples who underwent at least one IUI-intrauterine insemination cycle.

Exclusion Criteria:

* Couples who used donor sperm.
* Cases with missing core outcome data

Where it's running

• The Chinese University of Hong Kong
  Hong Kong, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.