Weight loss using the Mayo Clinic Diet
Weight Loss Through Mayo Clinic Diet; a Prospective Pilot Study
This study is testing whether the Mayo Clinic Diet can help people lose more than 5% of their weight and improve their overall health compared to regular weight loss methods.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 250 (estimated) |
| Ages | 18 Years to 64 Years |
| Sex | All |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT06862375 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of the Mayo Clinic Diet in achieving clinically significant weight loss of more than 5% compared to usual care. It also examines the feasibility, barriers to completion, and sustainability of the diet intervention at 24 and 52 weeks. Additionally, the study aims to assess changes in participants' body composition and quality of life following the intervention.
Who should consider this trial
Good fit: Ideal candidates for this study are non-pregnant males and females aged 18-64 with a BMI of 25 kg/m2 or higher.
Not a fit: Patients with a current diagnosis of cancer, diabetes, or those who have had weight loss surgery recently may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide an effective dietary approach for significant weight loss and improved quality of life for individuals with obesity.
How similar studies have performed: Other studies have shown success with dietary interventions for weight loss, making this approach both relevant and promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Males and females (non-pregnant) 18-64 * BMI \> or = to 25 kg/m2 * Ability to read and understand English. (as the Mayo Clinic Diet book and app are only available in English) Exclusion Criteria: * Have a current diagnosis of melanoma or cancer diagnosis * Currently breastfeeding * Pregnant, or planned to be pregnant within 6 months * Have a diagnosis of Type 1 or 2 Diabetes Mellitus * Had weight loss surgery within the last year * Currently participating in another lifestyle weight loss program or taking medications for weight loss * Have lost 5% or more of their weight in the last six months * Have a history of eating disorders * Have planned surgery in the next 6 months.
Where this trial is running
Rochester, Minnesota
- Mayo Clinic in Rochester — Rochester, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Tamim Rajjo — Mayo Clinic
- Study coordinator: Family Medicine Research Study Coordinators
- Email: RSTFMSC@mayo.edu
- Phone: 507-422-6823
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.