Weight-bearing CT of the patellofemoral joint and its link to knee pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project uses weight-bearing CT (WBCT) scans taken at 0° and 20° of knee flexion to quantify patellofemoral joint (PFJ) morphological metrics. Adults with either isolated anterior (PFJ) pain or symptomatic knee osteoarthritis will complete symptom and function assessments and undergo WBCT imaging. Investigators will compare imaging-derived structural measures to reported pain location, severity, and function to identify PFJ features associated with symptoms. Key exclusions include bilateral total knee arthroplasty, pregnancy, and inability to stand safely for the scan.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18
* Knee pain, falling into either of the two groups, i.e., PFJ pain (pain only in the anterior region of the knee) or symptomatic knee OA (pain in any other area of the knee, including the anterior region)

Exclusion Criteria:

* Bilateral total knee arthroplasty
* Pregnant
* Unable to stand safely for 2 minutes with support
* Any condition that the investigator identifies as inappropriate for participation (e.g., unable to participant in consent process, unsafe to stand on WBCT platform, etc.)

Where it's running

• University of Kansas Medical Center
  Kansas City, Kansas, United States Recruiting

Study contacts

• Principal investigator: Neil A Segal, MD, MS — University of Kansas Medical Center
• Study coordinator: Jessica Lee, PhD
• Email: jlee33@kumc.edu
• Phone: 913-574-0958

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.