Web-based therapy for depression

The Efficacy and Treatment Mechanisms of the Web-based Acceptance and Commitment Therapy for Patients with Major Depressive Disorder

NA · Gachon University · NCT06293781

This study is testing if online therapy called Acceptance and Commitment Therapy can help people with depression feel better by looking at how it affects their thinking and brain activity.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages19 Years to 65 Years
SexAll
SponsorGachon University (other)
Locations1 site (Incheon, Please Incheon)
Trial IDNCT06293781 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of web-based Acceptance and Commitment Therapy (ACT) for individuals diagnosed with Major Depressive Disorder. It is a randomized controlled trial that aims to assess changes in psychological flexibility and cognitive fusion among participants. Additionally, the study will utilize functional MRI to explore the underlying mechanisms of how web-based ACT may facilitate recovery from depression.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with Major Depressive Disorder.

Not a fit: Patients with serious medical issues, severe brain injuries, or those at high risk for suicide may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide an accessible and effective treatment option for individuals suffering from depression.

How similar studies have performed: Other studies have shown promise in using web-based therapies for mental health conditions, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who diagnosed major depressive disorder

Exclusion Criteria:

* Patients who have serious medical problems, metal implants in their bodies, severe brain injury or brain disease
* Women who were pregnant or nursing
* Patients at high risk for suicide

Where this trial is running

Incheon, Please Incheon

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Major Depressive Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.