Web-based support for pregnant women with depression in Eswatini

Effectiveness of a Web-based Psychoeducation on Antenatal Depression Help-seeking in Eswatini

Not applicable Interventional Taipei Medical University · NCT06390735

This study tests if an online support program can help pregnant women in Eswatini who are feeling depressed to seek help more effectively.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment214 (estimated)
Ages18 Years and up
SexFemale
SponsorTaipei Medical University Academic / other
Locations2 sites (Mbabane, Hhohho and 1 other locations)
Trial IDNCT06390735 on ClinicalTrials.gov

What this trial studies

This trial aims to evaluate the effectiveness of a web-based psychoeducation program designed to improve help-seeking intentions and behaviors among antenatal women experiencing probable depression in Eswatini. Participants will engage in a total of four sessions over two weeks, with their help-seeking behaviors assessed before, immediately after, and one month post-intervention. The study compares the psychoeducation program to a waitlist control group to determine its impact on mental health support-seeking during pregnancy.

Who should consider this trial

Good fit: Ideal candidates are pregnant women under 30 weeks of gestation, aged 18 or older, who exhibit probable depression and have access to a smartphone.

Not a fit: Patients currently receiving antidepressant treatment or enrolled in another trial may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly enhance the likelihood of antenatal women seeking help for depression, leading to better mental health outcomes for mothers and their children.

How similar studies have performed: Previous studies have shown promise in using web-based interventions for mental health support, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Less than 30 weeks of gestation,
* Aged 18 or above
* With probable depression (Edinburg Postnatal depression scale; EPDS \> 10)
* Has access to a smart phone
* Fluent in spoken and written Siswati or English (with at least secondary school education)
* Planning to remain in the country for the next 2 months
* Willing to share her dominant phone number with the study team
* Willing to participate in the intervention study

Exclusion Criteria:

* Antidepressants or other depression treatments
* Currently enrolled in another trial

Where this trial is running

Mbabane, Hhohho and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Help-Seeking BehaviorHelp-seeking IntentionAntenatal Depressionantenatal depressionWeb-based interventionsPsychoeducationRCTEswatini
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.