Clinical trial Recruiting at 2 sites Phase 2 Interventional Ages 18 and up

Web-based program to help head and neck cancer patients with swallowing exercises

Official title: Mobile Delivery of a Coping and Adherence Program for Head and Neck Cancer Patients Being Treated in Community Care Settings

Run by M.D. Anderson Cancer Center · NCT04003051 · Data updated 2026-11-12

This study tests whether a web-based program can help head and neck cancer patients stick to their swallowing exercises during radiation therapy to improve their recovery.

Quick facts

PhasePhase 2
Study typeInterventional
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorM.D. Anderson Cancer Center
Academic / other
Drugs / interventionsradiation
Locations2 sites (Fort Worth, Texas and 1 other locations)
StatusRecruiting
StartedMarch 18, 2019
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedOctober 6, 2026
Trial IDNCT04003051 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients receiving radiation treatment for throat cancer who can communicate in English or Spanish.

Probably not a fit

Patients not undergoing radiation therapy or those who cannot engage with the web-based platform may not benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This phase II trial evaluates the effectiveness of a web-based program called Project Prepare in assisting patients with head and neck cancer to adhere to swallowing and trismus exercises during radiation therapy. The program provides video demonstrations, patient stories, and practical tips to enhance recovery and manage side effects. Participants will engage with the platform over a 10-week period, with follow-up assessments at six months to measure improvements in swallowing function and adherence to exercises. The initiative aims to support underserved populations lacking access to specialized care.

Why it matters

Potential benefit: If successful, this program could significantly improve swallowing function and quality of life for patients undergoing treatment for head and neck cancer.

How similar studies have gone: Other studies have shown promise in using digital platforms for patient education and adherence, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Receiving radiation treatment with curative intent for throat cancer
* Can read and speak English or Spanish well enough to answer our questionnaires and understand our website content.

Where it's running

  • Texas Health Care-Otolaryngology and Plastic Surgery Associates
    Fort Worth, Texas, United States
    Recruiting
  • M D Anderson Cancer Center
    Houston, Texas, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.