Web and mobile program to help long-term breast cancer survivors manage late effects

A Web-based Tailored Intervention to Improve the Quality of Life of Long-term Breast Cancer Survivors. A Randomized Controlled Trial

Not applicable Interventional Fundacion Miguel Servet · NCT05322460

This web and mobile program will be tried to see if personalized, AI-driven guidance delivered through primary care helps women five or more years after breast cancer treatment manage physical, emotional, and social late effects.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment182 (estimated)
Ages18 Years to 99 Years
SexFemale
SponsorFundacion Miguel Servet Academic / other
Drugs / interventionschemotherapy
Locations1 site (Pamplona)
Trial IDNCT05322460 on ClinicalTrials.gov

What this trial studies

The project will design a personalized digital intervention (web/mobile) using algorithms to tailor content to long-term breast cancer survivors' needs, then pilot and test it in a randomized controlled trial following the Medical Research Council framework. Phase I involves expert-informed content design based on a review of survivors' needs; Phase II includes a pilot pretest–posttest; a full RCT will compare the web-based program delivered via primary care against usual primary care. Primary outcomes include quality of life and self-efficacy for managing late sequelae, collected with validated measures. The intervention aims to improve continuity between oncology and primary care by providing tailored self-management support remotely.

Who should consider this trial

Good fit: Women aged 18 or older who were diagnosed with breast cancer, completed active treatment more than five years ago, are currently disease-free, and are comfortable using the Internet are ideal candidates.

Not a fit: Men, people with recurrent or metastatic disease, those currently receiving active cancer treatment, or people who cannot use Spanish-language web/mobile tools may not benefit from this intervention.

Why it matters

Potential benefit: If successful, the program could improve survivors' quality of life and confidence in managing long-term physical and psychological effects while strengthening follow-up in primary care.

How similar studies have performed: Previous web-based survivorship and self-management programs have shown mixed but often promising improvements in quality of life and self-efficacy, while AI-tailored interventions in this specific population remain relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* having been diagnosed with breast cancer
* having completed active oncological treatments (chemotherapy and/or radiotherapy) in a period of time greater than five years,
* be free of disease at the time of data collection
* be a woman and over 18 years of age
* have knowledge of Internet use.

Exclusion Criteria:

* Women with a diagnosis of cancer other than breast cancer
* Recurrence of cancer or metastasis that causes a new treatment
* Being in active treatment for recurrence or new cancer
* Being a man

Where this trial is running

Pamplona

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Long-term Effects of Cancer TreatmentLong-term Effects Secondary to Cancer Therapy in AdultsCancer survivorsLong-Term Cancer SurvivorsLong Term Cancer SurvivorsSurvivorship
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.