Wearable robotic glove plus virtual reality to help hand recovery after stroke

Effects of Wearable Robotic and Virtual Reality-Assisted Interventions on Hand Function in Stroke Rehabilitation

NA · Medipol University · NCT07287059

This trial will test whether using a soft robotic glove together with a Leap Motion virtual-reality controller improves hand movement in adults with one-sided weakness after stroke.

Quick facts

PhaseNA
Study typeInterventional
Enrollment42 (estimated)
Ages30 Years to 60 Years
SexAll
SponsorMedipol University (other)
Locations1 site (Istanbul, Beykoz)
Trial IDNCT07287059 on ClinicalTrials.gov

What this trial studies

This is a multicenter randomized controlled trial comparing technology-assisted therapy using a soft robotic glove combined with a Leap Motion motion-tracking controller versus conventional neurodevelopmental therapy for upper-limb rehabilitation. Eligible participants are adults after stroke with preserved cognition and some active wrist extension who meet motor-function thresholds. Participants will be randomly assigned to receive the robotic/virtual-reality intervention or standard therapy and outcomes will focus on hand and upper-extremity motor function. The trial aims to increase voluntary movement quality and functional use of the affected hand through increased repetitive, task-oriented practice supported by wearable and motion-tracking technology.

Who should consider this trial

Good fit: Adults with post-stroke hemiplegia who can follow instructions (MMSE > 24), have some active wrist extension (> 10°), moderate motor recovery (Brunnstrom > 3, Fugl-Meyer UE > 22), and no severe spasticity (Modified Ashworth Scale < 3) are ideal candidates.

Not a fit: People with severe unilateral neglect, major visual or communication deficits, peripheral nerve injury to the arm, recent botulinum toxin to the affected limb, history of major upper-limb surgery, uncontrolled medical comorbidities, or a history of seizures are unlikely to be eligible or to benefit.

Why it matters

Potential benefit: If successful, this approach could improve hand movement and daily-function independence for people with post-stroke hemiplegia.

How similar studies have performed: Prior small trials and pilot studies of soft robotic gloves and virtual-reality motion tracking have reported promising gains in hand movement and practice intensity, but larger randomized trials are still limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical diagnosis of stroke
* Mini-Mental State Examination score \> 24
* Modified Ashworth Scale score \< 3
* Active wrist extension \> 10°
* Brunnstrom stage \> 3
* Fugl-Meyer Upper Extremity score \> 22

Exclusion Criteria:

* Presence of significant unilateral neglect
* Presence of significant visual deficits
* Communication disorders that interfere with assessment or intervention
* Peripheral nerve injury affecting the upper limb
* Botulinum toxin injection to the affected upper limb within the previous six months
* History of major orthopedic surgery of the affected upper limb
* Serious systemic comorbidities
* History of epileptic seizures

Where this trial is running

Istanbul, Beykoz

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Post-Stroke Hemiplegia, Stroke, Soft Robotic Glove, Leap Motion Controller, Rehabilitation, Hand Function

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.