Wearable robotic glove plus virtual reality to help hand recovery after stroke
Official title: Effects of Wearable Robotic and Virtual Reality-Assisted Interventions on Hand Function in Stroke Rehabilitation
Run by Medipol University · NCT07287059 · Data updated 2026-11-12
This trial will test whether using a soft robotic glove together with a Leap Motion virtual-reality controller improves hand movement in adults with one-sided weakness after stroke.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 30 Years to 60 Years |
| Sex | All |
| Enrollment | 42 (estimated) |
| Sponsor | Medipol University Academic / other |
| Locations | 1 site (Istanbul, Beykoz) |
| Status | Recruiting |
| Started | December 20, 2025 |
| Main results expected | May 15, 2026 |
| Study ends | June 15, 2026 |
| Registry record updated | January 28, 2026 |
| Trial ID | NCT07287059 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with post-stroke hemiplegia who can follow instructions (MMSE > 24), have some active wrist extension (> 10°), moderate motor recovery (Brunnstrom > 3, Fugl-Meyer UE > 22), and no severe spasticity (Modified Ashworth Scale < 3) are ideal candidates.
✕Probably not a fit
People with severe unilateral neglect, major visual or communication deficits, peripheral nerve injury to the arm, recent botulinum toxin to the affected limb, history of major upper-limb surgery, uncontrolled medical comorbidities, or a history of seizures are unlikely to be eligible or to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a multicenter randomized controlled trial comparing technology-assisted therapy using a soft robotic glove combined with a Leap Motion motion-tracking controller versus conventional neurodevelopmental therapy for upper-limb rehabilitation. Eligible participants are adults after stroke with preserved cognition and some active wrist extension who meet motor-function thresholds. Participants will be randomly assigned to receive the robotic/virtual-reality intervention or standard therapy and outcomes will focus on hand and upper-extremity motor function. The trial aims to increase voluntary movement quality and functional use of the affected hand through increased repetitive, task-oriented practice supported by wearable and motion-tracking technology.
Why it matters
Potential benefit: If successful, this approach could improve hand movement and daily-function independence for people with post-stroke hemiplegia.
How similar studies have gone: Prior small trials and pilot studies of soft robotic gloves and virtual-reality motion tracking have reported promising gains in hand movement and practice intensity, but larger randomized trials are still limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of stroke * Mini-Mental State Examination score \> 24 * Modified Ashworth Scale score \< 3 * Active wrist extension \> 10° * Brunnstrom stage \> 3 * Fugl-Meyer Upper Extremity score \> 22 Exclusion Criteria: * Presence of significant unilateral neglect * Presence of significant visual deficits * Communication disorders that interfere with assessment or intervention * Peripheral nerve injury affecting the upper limb * Botulinum toxin injection to the affected upper limb within the previous six months * History of major orthopedic surgery of the affected upper limb * Serious systemic comorbidities * History of epileptic seizures
Where it's running
-
Istanbul Medipol University, Physiotherapy and Rehabilitation Department
Istanbul, Beykoz, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Taha A Erdogan, MSc, Physiotherapist
- Email: tahayberkk@gmail.com
- Phone: +905546235525
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.