We-INtervention for Chinese male couples where one partner is HIV-positive and the other is HIV-negative

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The randomized trial will enroll 160 Chinese HIV-serodiscordant male couples (320 individuals) and assign them 1:1 to the three-session We-INtervention or to a control condition receiving health information pamphlets. In the intervention arm both partners receive sessions focused on relationship dynamics, coping with stigma, and health-promoting behaviors delivered separately to each partner. Outcomes include stigma perception, quality of life, psychological well-being, relationship satisfaction, HIV-related behaviors, and mediators that may explain any effects. The trial expands on a pilot RCT that showed feasibility, acceptability, cultural sensitivity, and preliminary benefit and will be run at community sites in Xiamen, Guangzhou, and Shenzhen.

Why it matters

Who can join: the full rules

Inclusion criteria:

1. both partners are male,
2. both partners are aged 18 or above,
3. both partners report being in a committed relationship for at least 3 months,
4. one partner is HIV-seropositive and the other partner is HIV-seronegative (i.e., serodiscordant couple),
5. both partners have disclosed their serostatus to each other, and
6. both partners are willing to participate in this study.

Exclusion criteria:

1. either partner is unable to complete the assessment due to a low education level or to physical or psychological constraints and
2. either partner has been diagnosed with another chronic disease (e.g., cancer and coronary heart disease).

Where it's running

• Fangzhouai Garden
  Xiamen, Fujian, China Recruiting
• Guangzhou Yuele Healthcare Service Center
  Guangzhou, Guangdong, China Recruiting
• Community Always There
  Shenzhen, Guangdong, China Recruiting
• Jin Tang Six-Color Rainbow Healthcare Center
  Chengdu, Sichuan, China Recruiting

Study contacts

• Study coordinator: Nancy Xiaonan Yu, PhD
• Email: nancy.yu@cityu.edu.hk
• Phone: 34429436

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.