Walking exercise and CPAP for patients with sleep apnea and fatty liver
Impact of Free Walking Exercise on Obstructive Sleep Apnea Patients With Non-alcoholic Fatty Liver on Liver Enzymes, Degree of Exhaustion, and Quality of Sleep
This study is testing if adding a walking exercise program to CPAP treatment can help people with sleep apnea and fatty liver feel less tired and improve their sleep and liver health.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 40 Years to 65 Years |
| Sex | All |
| Sponsor | Ahram Canadian University Academic / other |
| Locations | 1 site (Giza) |
| Trial ID | NCT06508190 on ClinicalTrials.gov |
What this trial studies
This research evaluates the effects of continuous positive airway pressure (CPAP) combined with a walking exercise program on fatigue severity, liver enzyme levels, and sleep quality in patients suffering from non-alcoholic fatty liver disease and obstructive sleep apnea. A total of forty patients will be enrolled and divided into two groups: one receiving only CPAP treatment and the other receiving both CPAP and a walking exercise regimen. The study aims to determine if the addition of physical activity can enhance the benefits of CPAP therapy.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with obstructive sleep apnea and non-alcoholic fatty liver disease who have a body mass index (BMI) of less than 35 kg/m2.
Not a fit: Patients with conditions such as liver transplantation, alcoholic fatty liver, or significant cardiac and renal problems may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve the quality of life and health outcomes for patients with both obstructive sleep apnea and non-alcoholic fatty liver disease.
How similar studies have performed: While the specific combination of CPAP and walking exercise in this context is novel, similar studies have shown positive outcomes with exercise interventions in patients with sleep apnea.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * The body mass index (BMI) \< 35 kg/m2. * obstructive sleep apnea patients with fatty liver Exclusion Criteria: * liver transplantation , alcoholic fatty liver, antipsychotic medications, bariatric surgery; cardiac , renal problem , liver cancer ; pregnancy,orthopedic problems, systemic diseases, respiratory dysfunctions, neurological dysfunctions.
Where this trial is running
Giza
- Ahram canadian university — Giza, Egypt (Recruiting)
Study contacts
- Principal investigator: El-Hadidy Hagar — Faculty of Physical Therapy, Ahram Canadian University (ACU), Giza, Egypt
- Study coordinator: El-Hadidy Hagar, PHD
- Email: hagarhadidy2016@gmail.com
- Phone: 00201007453552
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.